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MED12 Antikörper (AA 251-350) (Biotin)

MED12 Reaktivität: Maus, Ratte ELISA, WB, IHC (p), IHC (fro) Wirt: Kaninchen Polyclonal Biotin
Produktnummer ABIN5675221
  • Target Alle MED12 Antikörper anzeigen
    MED12 (Mediator Complex Subunit 12 (MED12))
    Bindungsspezifität
    • 14
    • 5
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 251-350
    Reaktivität
    • 28
    • 24
    • 16
    • 1
    • 1
    • 1
    • 1
    Maus, Ratte
    Wirt
    • 38
    • 1
    • 1
    Kaninchen
    Klonalität
    • 39
    • 1
    Polyklonal
    Konjugat
    • 17
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser MED12 Antikörper ist konjugiert mit Biotin
    Applikation
    • 24
    • 14
    • 13
    • 13
    • 8
    • 5
    • 3
    • 3
    • 2
    • 2
    • 1
    ELISA, Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
    Kreuzreaktivität
    Maus, Ratte
    Homologie
    Human,Cow,Sheep,Pig,Rabbit
    Aufreinigung
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human MED12/Trap230
    Isotyp
    IgG
    Top Product
    Discover our top product MED12 Primärantikörper
  • Applikationshinweise
    WB 1:300-5000
    IHC-P 1:200-400
    IHC-F 1:100-500
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C for 12 months.
    Haltbarkeit
    12 months
  • Target
    MED12 (Mediator Complex Subunit 12 (MED12))
    Andere Bezeichnung
    MED12/Trap230 (MED12 Produkte)
    Synonyme
    ARC240 antikoerper, CAGH45 antikoerper, FGS1 antikoerper, HOPA antikoerper, MED12S antikoerper, OHDOX antikoerper, OKS antikoerper, OPA1 antikoerper, TNRC11 antikoerper, TRAP230 antikoerper, 230kDa antikoerper, Mopa antikoerper, OPA-1 antikoerper, Tnrc11 antikoerper, Trap230 antikoerper, mediator complex subunit 12 antikoerper, MED12 antikoerper, Med12 antikoerper, med12 antikoerper
    Hintergrund

    Synonyms: Mediator of RNA polymerase II transcription subunit 12, MED12, Activator-recruited cofactor 240 kDa component, ARC240, CAG repeat protein 45 Mediator complex subunit 12, OPA-containing protein, Thyroid hormone receptor-associated protein complex 230 kDa component, Trap230, Trinucleotide repeat-containing gene 11 protein, MED12, ARC240, CAGH45, HOPA, KIAA0192, TNRC11, TRAP230

    Background: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. This subunit may specifically regulate transcription of targets of the Wnt signaling pathway and SHH signaling pathway.

    Gen-ID
    9968
    UniProt
    Q93074
    Pathways
    Intracellular Steroid Hormone Receptor Signaling Pathway, Nuclear Hormone Receptor Binding, Stem Cell Maintenance, Chromatin Binding, Regulation of Lipid Metabolism by PPARalpha, Tube Formation
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