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ERO1L Antikörper (AA 321-420) (Biotin)

ERO1L Reaktivität: Human WB, ELISA Wirt: Kaninchen Polyclonal Biotin
Produktnummer ABIN5675520
  • Target Alle ERO1L Antikörper anzeigen
    ERO1L (ERO1-Like Protein alpha (ERO1L))
    Bindungsspezifität
    • 15
    • 7
    • 6
    • 6
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 321-420
    Reaktivität
    • 43
    • 4
    • 4
    Human
    Wirt
    • 37
    • 5
    • 1
    Kaninchen
    Klonalität
    • 40
    • 2
    Polyklonal
    Konjugat
    • 21
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser ERO1L Antikörper ist konjugiert mit Biotin
    Applikation
    • 43
    • 21
    • 19
    • 16
    • 4
    • 2
    • 2
    • 1
    Western Blotting (WB), ELISA
    Kreuzreaktivität
    Human
    Homologie
    Mouse,Rat,Rabbit
    Aufreinigung
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human ERO1L
    Isotyp
    IgG
    Top Product
    Discover our top product ERO1L Primärantikörper
  • Applikationshinweise
    WB 1:300-5000
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C for 12 months.
    Haltbarkeit
    12 months
  • Target
    ERO1L (ERO1-Like Protein alpha (ERO1L))
    Andere Bezeichnung
    ERO1L (ERO1L Produkte)
    Synonyme
    ERO1-L antikoerper, ero1-alpha antikoerper, ero1lb antikoerper, ERO1L antikoerper, ero1l antikoerper, ERO1-alpha antikoerper, ERO1A antikoerper, zgc:63959 antikoerper, endoplasmic reticulum oxidoreductase alpha L homeolog antikoerper, endoplasmic reticulum oxidoreductase 1 alpha antikoerper, endoplasmic reticulum oxidoreductase alpha antikoerper, ERO1-like (S. cerevisiae) antikoerper, ero1a.L antikoerper, ERO1A antikoerper, ero1a antikoerper, Ero1l antikoerper, Ero1a antikoerper
    Hintergrund

    Synonyms: ERO1-like protein alpha, ERO1A, ERO1-L, ERO1-L-alpha, Endoplasmic oxidoreductin-1-like protein, Endoplasmic reticulum oxidoreductase alpha, Oxidoreductin-1-L-alpha, ERO1L

    Background: Oxidoreductase involved in disulfide bond formation in the endoplasmic reticulum. Efficiently reoxidizes P4HB/PDI, the enzyme catalyzing protein disulfide formation, in order to allow P4HB to sustain additional rounds of disulfide formation. Following P4HB reoxidation, passes its electrons to molecular oxygen via FAD, leading to the production of reactive oxygen species (ROS) in the cell. Required for the proper folding of immunoglobulins. Involved in the release of the unfolded cholera toxin from reduced P4HB/PDI in case of infection by V.cholerae, thereby playing a role in retrotranslocation of the toxin. Plays an important role in ER stress-induced, CHOP-dependent apoptosis by activating the inositol 1,4,5-trisphosphate receptor IP3R1.

    Gen-ID
    30001
    UniProt
    Q96HE7
    Pathways
    Peptide Hormone Metabolism, ER-Nucleus Signaling, Brown Fat Cell Differentiation
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