EXD2 Antikörper (AA 351-621)

Produktnummer ABIN5675755

Produktdetails anti-EXD2 Antikörper

Target: EXD2 (Exonuclease 3'-5' Domain Containing 2 (EXD2))

Bindungsspezifität: AA 351-621

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser EXD2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC)

Spezifität: WB shows isoform 2

Kreuzreaktivität: Human, Maus, Ratte

Homologie: Dog,Cow,Sheep,Pig,Horse

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human EXD2

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Details zu EXD2

Target: EXD2 (Exonuclease 3'-5' Domain Containing 2 (EXD2))

Andere Bezeichnung: EXD2 (EXD2 Produkte)

Synonyme: C14orf114 antikoerper, EXDL2 antikoerper, 4930539P14Rik antikoerper, C85658 antikoerper, Exdl2 antikoerper, RGD1311087 antikoerper, exd2-b antikoerper, exdl2 antikoerper, fi72h12 antikoerper, wu:fi72h12 antikoerper, zgc:175195 antikoerper, exd2 antikoerper, exd2-a antikoerper, exonuclease 3'-5' domain containing 2 antikoerper, exonuclease 3'-5' domain containing 2 b antikoerper, EXD2 antikoerper, Exd2 antikoerper, exd2.S antikoerper, exd2 antikoerper, exd2.L antikoerper

Hintergrund:

Synonyms: Exonuclease 3'-5' domain-containing protein 2, EXD2, C14orf114, EXDL2

Background: Exonuclease required for double-strand breaks resection and efficient homologous recombination. Plays a key role in controlling the initial steps of chromosomal break repair, it is recruited to chromatin in a damage-dependent manner and functionally interacts with the MRN complex to accelerate resection through its 3'-5' exonuclease activity, which efficiently processes double-stranded DNA substrates containing nicks.

Gen-ID: 55218

UniProt: Q9NVH0