EXD2 Antikörper (AA 351-621) (Biotin)
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- Target Alle EXD2 Produkte
- EXD2 (Exonuclease 3'-5' Domain Containing 2 (EXD2))
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Bindungsspezifität
- AA 351-621
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Reaktivität
- Human, Maus, Ratte
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser EXD2 Antikörper ist konjugiert mit Biotin
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Applikation
- Western Blotting (WB), ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Spezifität
- WB shows isoform 2
- Kreuzreaktivität
- Human, Maus, Ratte
- Homologie
- Dog,Cow,Sheep,Pig,Horse
- Aufreinigung
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic peptide derived from human EXD2
- Isotyp
- IgG
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- Applikationshinweise
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WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500 - Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Konservierungsmittel
- ProClin
- Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20°C for 12 months.
- Haltbarkeit
- 12 months
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- Target
- EXD2 (Exonuclease 3'-5' Domain Containing 2 (EXD2))
- Andere Bezeichnung
- EXD2 (EXD2 Produkte)
- Synonyme
- C14orf114 antikoerper, EXDL2 antikoerper, 4930539P14Rik antikoerper, C85658 antikoerper, Exdl2 antikoerper, RGD1311087 antikoerper, exd2-b antikoerper, exdl2 antikoerper, fi72h12 antikoerper, wu:fi72h12 antikoerper, zgc:175195 antikoerper, exd2 antikoerper, exd2-a antikoerper, exonuclease 3'-5' domain containing 2 antikoerper, exonuclease 3'-5' domain containing 2 b antikoerper, EXD2 antikoerper, Exd2 antikoerper, exd2.S antikoerper, exd2 antikoerper, exd2.L antikoerper
- Hintergrund
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Synonyms: Exonuclease 3'-5' domain-containing protein 2, EXD2, C14orf114, EXDL2
Background: Exonuclease required for double-strand breaks resection and efficient homologous recombination. Plays a key role in controlling the initial steps of chromosomal break repair, it is recruited to chromatin in a damage-dependent manner and functionally interacts with the MRN complex to accelerate resection through its 3'-5' exonuclease activity, which efficiently processes double-stranded DNA substrates containing nicks.
- Gen-ID
- 55218
- UniProt
- Q9NVH0
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