NQO2 Antikörper

Produktnummer ABIN567621

Produktdetails anti-NQO2 Antikörper

Target: NQO2

Reaktivität: Human, Maus

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser NQO2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Enzyme Immunoassay (EIA)

Spezifität: The antibody recognizes human and mouse NQO2. Other species not tested.

Aufreinigung: Protein-G affinity chromatography

Klon: AT1E3

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1.0 mg/mL

Buffer: PBS, pH 7.4, containing 0.09 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Details zu NQO2

Target: NQO2

Andere Bezeichnung: NQO2 (NQO2 Produkte)

Synonyme: DHQV antikoerper, DIA6 antikoerper, NMOR2 antikoerper, QR2 antikoerper, NMO2 antikoerper, Nmor2 antikoerper, Ox2 antikoerper, N-ribosyldihydronicotinamide:quinone reductase 2 antikoerper, N-ribosyldihydronicotinamide quinone reductase 2 antikoerper, NQO2 antikoerper, Nqo2 antikoerper

Hintergrund: Quinone oxidoreductase (NQO1 and NQO2) are cytosolic proteins that catalyze metabolic redaction of quinines and derivates.NQO2 is inhibited by flavones such as quercetin. Also benzo(a)pyrene is another known inhibitor of NQO2. Even though overlapping substrates specificities have been observed for NQO1 and NQO2, such as for CB1954 activation, significant differences exist in relative affinities for the various substrates.The detoxification role of NQO2 has not been found, and it has no known endogenous biological substrates. However, NQO1 plays an important role in the detoxification of various endogenous and exogenous quinones, including estrogen quinines. Also NQO2 has a melatonin-binding site, which may explain the anti-oxidant role of melatonin related with circadian rhythm.Synonyms: NMOR2, NRH dehydrogenase [quinone] 2, NRH:quinone oxidoreductase 2, Ribosyldihydronicotinamide dehydrogenase [quinone]

Gen-ID: 4835