Cyclin E1 Antikörper
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- Target Alle Cyclin E1 (CCNE1) Antikörper anzeigen
- Cyclin E1 (CCNE1)
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Reaktivität
- Human
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Wirt
- Maus
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Klonalität
- Monoklonal
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Konjugat
- Dieser Cyclin E1 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Spezifität
- This antibody reacts with Cyclin E (50 kDa) on Western blotting. This monoclonal antibody may nonspecifically react with macrophages, endothelial cells and some stromal cells in Immunohistochemistry.
- Aufreinigung
- Protein-A Agarose Chromatography of hybridoma supernatant.
- Immunogen
- Human recombinant full length His-Cyclin E.
- Klon
- HE12
- Isotyp
- IgG1
- Top Product
- Discover our top product CCNE1 Primärantikörper
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anti-Cyclin E1 (CCNE1) (AA 10-176) antibody
CCNE1 Reaktivität: Human WB, IHC, StM Wirt: Maus Monoclonal CCNE1-2460 unconjugated
anti-Cyclin E1 (CCNE1) (AA 1-100) antibodyCCNE1 Reaktivität: Human IHC, ELISA, FACS Wirt: Maus Monoclonal 1C8D4 unconjugated
anti-Cyclin E1 (CCNE1) (AA 307-410) antibodyCCNE1 Reaktivität: Human ELISA, FACS Wirt: Maus Monoclonal 5F8C5 unconjugated
anti-Cyclin E1 (CCNE1) (AA 375-411) antibodyCCNE1 Reaktivität: Human, Maus, Ratte WB, ELISA, FACS, IHC (p), IF (cc), IF (p), IHC (fro) Wirt: Kaninchen Polyclonal unconjugated
anti-Cyclin E1 (CCNE1) (AA 1-410) antibodyCCNE1 Reaktivität: Human WB, PLA Wirt: Kaninchen Polyclonal unconjugated
anti-Cyclin E1 (CCNE1) (Thr395) antibodyCCNE1 Reaktivität: Human WB, IHC, ELISA, IF Wirt: Kaninchen Polyclonal unconjugated
anti-Cyclin E1 (CCNE1) antibodyCCNE1 Reaktivität: Human IHC, ELISA, IF Wirt: Kaninchen Monoclonal 3A5 unconjugated Recombinant Antibody
anti-Cyclin E1 (CCNE1) (AA 373-402), (C-Term) antibodyCCNE1 Reaktivität: Human WB, FACS, IHC (p) Wirt: Kaninchen Polyclonal RB07335 unconjugated
anti-Cyclin E1 (CCNE1) (AA 1-410) antibodyCCNE1 Reaktivität: Human WB, IF Wirt: Maus Polyclonal unconjugated
anti-Cyclin E1 (CCNE1) (C-Term) antibodyCCNE1 Reaktivität: Human, Maus, Ratte WB, IHC, ELISA, IF, ICC Wirt: Kaninchen Polyclonal unconjugated
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- Applikationshinweise
- Optimal working dilution should be determined by the investigator.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Konzentration
- 1.0 mg/mL
- Buffer
- PBS, pH 7.2 containing 50 % Glycerol without preservatives.
- Konservierungsmittel
- Without preservative
- Handhabung
- Avoid repeated freezing and thawing.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store the antibody (in aliquots) at -20 °C.
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- Target
- Cyclin E1 (CCNE1)
- Andere Bezeichnung
- Cyclin E1 (CCNE1 Produkte)
- Hintergrund
- Cyclin E, a positive regulator of the cell cycle, controls the transition of cells from G1 to S phase. Cyclin E forms a complex with Cdk2, the active kinase follows cyclin D/Cdk4 in progressively phosphorylating pRb, releasing it from members of the E2F family. E2F transcrIPPtion factors in turn activate a set of target genes that are essential for entry into S phase. Deregulation of the G1-S checkpoint contributes to uncontrolled cell division, a hallmark of cancer. Cyclin E overexpression and deregulation have been shown in several cancers including breast, colorectal, gastric and lungSynonyms: CCNE, CCNE1, Cyclin-E1
- Gen-ID
- 898
- NCBI Accession
- NP_001229
- UniProt
- P24864
- Pathways
- Zellzyklus, Intracellular Steroid Hormone Receptor Signaling Pathway, Nuclear Hormone Receptor Binding, Mitotic G1-G1/S Phases
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