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TXNIP Antikörper

TXNIP Reaktivität: Human, Maus, Ratte WB, IP, IHC (p) Wirt: Maus Monoclonal JY2 unconjugated
Produktnummer ABIN567794
  • Target Alle TXNIP Antikörper anzeigen
    TXNIP (Thioredoxin Interacting Protein (TXNIP))
    Reaktivität
    • 62
    • 47
    • 32
    • 5
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    Human, Maus, Ratte
    Wirt
    • 72
    • 4
    Maus
    Klonalität
    • 64
    • 12
    Monoklonal
    Konjugat
    • 30
    • 7
    • 6
    • 5
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser TXNIP Antikörper ist unkonjugiert
    Applikation
    • 52
    • 27
    • 15
    • 14
    • 14
    • 7
    • 7
    • 5
    • 4
    • 3
    • 3
    • 1
    • 1
    Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Spezifität
    This antibody reacts with Txnip/VDUP1 (50 kDa) on Western blotting and Immunoprecipitation.
    Aufreinigung
    Protein-A Agarose Chromatography of hybridoma supernatant.
    Immunogen
    Human recombinant VDUP-1/Txnip.
    Klon
    JY2
    Isotyp
    IgG1
    Top Product
    Discover our top product TXNIP Primärantikörper
  • Applikationshinweise
    Optimal working dilution should be determined by the investigator.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Konzentration
    1.0 mg/mL
    Buffer
    PBS, pH 7.2 containing 50 % Glycerol without preservatives.
    Konservierungsmittel
    Without preservative
    Handhabung
    Avoid repeated freezing and thawing.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store the antibody (in aliquots) at -20 °C.
  • Target
    TXNIP (Thioredoxin Interacting Protein (TXNIP))
    Andere Bezeichnung
    TXNIP / VDUP1 (TXNIP Produkte)
    Hintergrund
    Vitamin D3 up-regulated protein 1 (VDUP-1), also called Thioredoxin (TRX)-interacting protein, is an endogenous inhibitor of TRX. Redox-dependent regulation of VDUP-1 by mitogenic factors through Reactive oxygen species (ROS) and the specific binding of VDUP-1 to the redox-sensitive cysteine-sulfide center of TRX modulate intracellular levels of ROS and the mitogenic activity of TRX. It has been reported that Txnip plays important roles in diverse cellular processes, including the regulation of cellular redox balance, apoptosis, proliferation, and differentiation.Synonyms: Thioredoxin-binding protein 2, Thioredoxin-interacting protein, Vitamin D3 up-regulated protein 1
    Gen-ID
    10628
    NCBI Accession
    NP_006463
    UniProt
    Q9H3M7
    Pathways
    Protein targeting to Nucleus, Platelet-derived growth Factor Receptor Signaling, Inflammasome
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