HBSAg Antikörper

Produktnummer ABIN567926

Produktdetails anti-HBSAg Antikörper

Target: HBSAg (HBsAg) (Hepatitis B Virus Surface Antigen (HBsAg))

Reaktivität: Hepatitis B Virus (HBV)

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser HBSAg Antikörper ist unkonjugiert

Applikation: Enzyme Immunoassay (EIA), ELISA (Detection)

Aufreinigung: Protein G Chromatography.

Immunogen: Recombinant HBsAg of ayw subtype

Klon: Hs41

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 10.8 mg/mL (OD280nm, E0.1%=1.4)

Buffer: PBS, pH 7.4 containing 0.09 % Sodiumm Azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: Store the antibody undiluted 2-8 °C.

Details zu HBSAg

Target: HBSAg (HBsAg) (Hepatitis B Virus Surface Antigen (HBsAg))

Andere Bezeichnung: Hepatitis B Surface Antigen / HBsAg (HBsAg Produkte)

Substanzklasse: Viral Protein

Hintergrund: Hepatitis B Virus (HBV) infection induces a disease state characterized by liver damage, inflammation and viral persistence. Infection also increases the risk of hepatocellular carcinoma. HBV belongs to the Hepadnaviridae family of viruses. Its genome consists of partially double stranded circular DNA. The DNA is enclosed in a nucleocapsid, or core antigen (HBcAg), which is surrounded by a spherical envelope (surface antigen or HBsAg). The core antigen shares its sequences with the e antigen (HBeAg) but no cross reactivity between the two proteins has been observed. The HBV genome also encodes a DNA polymerase that also acts as a reverse transcriptase. Hepatitis B infection is normally diagnosed from serological tests that detect HBsAg but as the disease progresses this antigen may no longer be present in the blood and tests for HBcAg are used. If HBsAg can be detected in the blood for longer than six months, chronic hepatitis B is diagnosed. The antigenic determinant of the protein moiety of the HBsAg determines specific characteristics of different serotypes and provides the basis of immunodetection. HBsAg has antigenic heterogeneity, specifically, two pairs of sub specific determinants, d/y and w/r allow the following combinations: adw, ayw, adr, ayr.Synonyms: HBV surface antigen, Hepatitis B Virus