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TIM3 Antikörper (AA 229-410)

TIM 3 Reaktivität: Human WB, FACS, ELISA, IHC, ICC, Neut Wirt: Maus Monoclonal 1H6A1 unconjugated
Produktnummer ABIN5684060
  • Target Alle TIM3 (TIM 3) Antikörper anzeigen
    TIM3 (TIM 3) (Hepatitis A Virus Cellular Receptor 2 (TIM 3))
    Bindungsspezifität
    • 19
    • 7
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 229-410
    Reaktivität
    • 75
    • 42
    • 4
    • 3
    • 2
    • 1
    • 1
    Human
    Wirt
    • 49
    • 32
    • 28
    • 2
    • 1
    Maus
    Klonalität
    • 65
    • 46
    • 1
    Monoklonal
    Konjugat
    • 62
    • 10
    • 10
    • 9
    • 8
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser TIM3 Antikörper ist unkonjugiert
    Applikation
    • 49
    • 46
    • 35
    • 24
    • 15
    • 7
    • 7
    • 5
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Flow Cytometry (FACS), ELISA, Immunohistochemistry (IHC), Immunocytochemistry (ICC), Neutralization (Neut)
    Aufreinigung
    purified
    Immunogen
    Purified recombinant fragment of human TIM3 (AA: 224-301) expressed in E. coli.
    Klon
    1H6A1
    Isotyp
    IgG1
    Top Product
    Discover our top product TIM 3 Primärantikörper
  • Applikationshinweise
    ELISA: 1:10000, WB: 1:500 - 1:2000, ICC: N/A, FCM: 1:200 - 1:400, IHC: N/A
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    Purified antibody in PBS with 0.05 % sodium azide
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C/-20 °C
    Informationen zur Lagerung
    4°C, -20°C for long term storage
  • Target
    TIM3 (TIM 3) (Hepatitis A Virus Cellular Receptor 2 (TIM 3))
    Andere Bezeichnung
    TIM3 (TIM 3 Produkte)
    Synonyme
    HAVCR2 antikoerper, MGC140131 antikoerper, HAVcr-2 antikoerper, KIM-3 antikoerper, TIM3 antikoerper, TIMD-3 antikoerper, TIMD3 antikoerper, Tim-3 antikoerper, TIM-3 antikoerper, Tim3 antikoerper, Timd3 antikoerper, tim3 antikoerper, hepatitis A virus cellular receptor 2 antikoerper, HAVCR2 antikoerper, Havcr2 antikoerper
    Substanzklasse
    Virus
    Hintergrund

    Description: The protein encoded by this gene belongs to the immunoglobulin superfamily, and TIM family of proteins. CD4-positive T helper lymphocytes can be divided into types 1 (Th1) and 2 (Th2) on the basis of their cytokine secretion patterns. Th1 cells are involved in cell-mediated immunity to intracellular pathogens and delayed-type hypersensitivity reactions, whereas, Th2 cells are involved in the control of extracellular helminthic infections and the promotion of atopic and allergic diseases. This protein is a Th1-specific cell surface protein that regulates macrophage activation, and inhibits Th1-mediated auto- and alloimmune responses, and promotes immunological tolerance.

    Aliases: HAVCR2, CD366, KIM-3, TIMD3, Tim-3, TIMD-3, HAVcr-2

    Molekulargewicht
    33.4 kDa
    Gen-ID
    84868
    HGNC
    550
    Pathways
    Regulation of Lipid Metabolism by PPARalpha, Cancer Immune Checkpoints
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