ITGA2 Antikörper (AA 994-1132)
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- Target Alle ITGA2 Antikörper anzeigen
- ITGA2 (Integrin alpha 2 (ITGA2))
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Bindungsspezifität
- AA 994-1132
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Reaktivität
- Human
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Wirt
- Maus
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Klonalität
- Monoklonal
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Konjugat
- Dieser ITGA2 Antikörper ist unkonjugiert
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Applikation
- Flow Cytometry (FACS), Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunocytochemistry (ICC), Neutralization (Neut)
- Aufreinigung
- purified
- Immunogen
- Purified recombinant fragment of human CD49B (AA: extra 994-1132) expressed in E. coli.
- Klon
- 8A11A2
- Isotyp
- IgG1
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- Applikationshinweise
- ELISA: 1:10000, WB: 1:500 - 1:2000, ICC: 1:100 - 1:500, FCM: 1:200 - 1:400, IHC: N/A
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
- Purified antibody in PBS with 0.05 % sodium azide
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C/-20 °C
- Informationen zur Lagerung
- 4°C, -20°C for long term storage
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- Target
- ITGA2 (Integrin alpha 2 (ITGA2))
- Andere Bezeichnung
- CD49B (ITGA2 Produkte)
- Synonyme
- BR antikoerper, CD49B antikoerper, GPIa antikoerper, HPA-5 antikoerper, VLA-2 antikoerper, VLAA2 antikoerper, DX5 antikoerper, integrin subunit alpha 2 antikoerper, integrin alpha 2 antikoerper, ITGA2 antikoerper, Itga2 antikoerper
- Hintergrund
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Description: This gene encodes the alpha subunit of a transmembrane receptor for collagens and related proteins. The encoded protein forms a heterodimer with a beta subunit and mediates the adhesion of platelets and other cell types to the extracellular matrix. Loss of the encoded protein is associated with bleeding disorder platelet-type 9. Antibodies against this protein are found in several immune disorders, including neonatal alloimmune thrombocytopenia. This gene is located adjacent to a related alpha subunit gene. Alternative splicing results in multiple transcript variants.
Aliases: ITGA2, BR, GPIa, HPA-5, VLA-2, VLAA2
- Molekulargewicht
- 129.3 kDa
- Gen-ID
- 3673
- HGNC
- 9882
- Pathways
- CXCR4-mediated Signaling Events, Smooth Muscle Cell Migration, Integrin Complex
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