CD42b Antikörper (AA 17-183)

Produktnummer ABIN5684108

Produktdetails anti-CD42b Antikörper

Target: CD42b (GP1BA) (Glycoprotein Ib (Platelet), alpha Polypeptide (GP1BA))

Bindungsspezifität: AA 17-183

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser CD42b Antikörper ist unkonjugiert

Applikation: Flow Cytometry (FACS), Western Blotting (WB), ELISA

Verwendungszweck: CD42B Antibody

Aufreinigung: Purified antibody

Immunogen: Purified recombinant fragment of human CD42B (AA: 17-183) expressed in E. Coli.

Klon: 6H6B11

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise:

ELISA: 1/10000

FCM: 1/200 - 1/400

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Details zu CD42b

Target: CD42b (GP1BA) (Glycoprotein Ib (Platelet), alpha Polypeptide (GP1BA))

Andere Bezeichnung: CD42B (GP1BA Produkte)

Synonyme: BDPLT1 antikoerper, BDPLT3 antikoerper, BSS antikoerper, CD42B antikoerper, CD42b-alpha antikoerper, DBPLT3 antikoerper, GP1B antikoerper, GPIbA antikoerper, VWDP antikoerper, GP1BA antikoerper, GPIba antikoerper, GPIbalpha antikoerper, glycoprotein Ib platelet alpha subunit antikoerper, glycoprotein Ib (platelet), alpha polypeptide antikoerper, glycoprotein 1b, alpha polypeptide antikoerper, GP1BA antikoerper, Gp1ba antikoerper

Hintergrund:

Description: Glycoprotein Ib (GP Ib) is a platelet surface membrane glycoprotein composed of a heterodimer, an alpha chain and a beta chain, that is linked by disulfide bonds. The Gp Ib functions as a receptor for von Willebrand factor (VWF). The complete receptor complex includes noncovalent association of the alpha and beta subunits with platelet glycoprotein IX and platelet glycoprotein V. The binding of the GP Ib-IX-V complex to VWF facilitates initial platelet adhesion to vascular subendothelium after vascular injury, and also initiates signaling events within the platelet that lead to enhanced platelet activation, thrombosis, and hemostasis. This gene encodes the alpha subunit. Mutations in this gene result in Bernard-Soulier syndromes and platelet-type von Willebrand disease. The coding region of this gene is known to contain a polymophic variable number tandem repeat (VNTR) domain that is associated with susceptibility to nonarteritic anterior ischemic optic neuropathy.

Aliases: GP1BA, BSS, GP1B, VWDP, GPIbA, BDPLT1, BDPLT3, DBPLT3, GPIbalpha, CD42b-alpha

Molekulargewicht: 71.5kDa

Gen-ID: 2811

HGNC: 2811