CD42b Antikörper (AA 17-183)
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- Target Alle CD42b (GP1BA) Antikörper anzeigen
- CD42b (GP1BA) (Glycoprotein Ib (Platelet), alpha Polypeptide (GP1BA))
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Bindungsspezifität
- AA 17-183
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Reaktivität
- Human
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Wirt
- Maus
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Klonalität
- Monoklonal
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Konjugat
- Dieser CD42b Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (IHC), ELISA, Immunocytochemistry (ICC), Neutralization (Neut)
- Aufreinigung
- purified
- Immunogen
- Purified recombinant fragment of human CD42B (AA: extra 17-183) expressed in E. coli.
- Klon
- 6H6H10
- Isotyp
- IgG1
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- Applikationshinweise
- ELISA: 1:10000, WB: 1:500 - 1:2000, ICC: N/A, FCM: 1:200 - 1:400, IHC: N/A
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
- Purified antibody in PBS with 0.05 % sodium azide
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C/-20 °C
- Informationen zur Lagerung
- 4°C, -20°C for long term storage
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- Target
- CD42b (GP1BA) (Glycoprotein Ib (Platelet), alpha Polypeptide (GP1BA))
- Andere Bezeichnung
- CD42B (GP1BA Produkte)
- Synonyme
- BDPLT1 antikoerper, BDPLT3 antikoerper, BSS antikoerper, CD42B antikoerper, CD42b-alpha antikoerper, DBPLT3 antikoerper, GP1B antikoerper, GPIbA antikoerper, VWDP antikoerper, GP1BA antikoerper, GPIba antikoerper, GPIbalpha antikoerper, glycoprotein Ib platelet alpha subunit antikoerper, glycoprotein Ib (platelet), alpha polypeptide antikoerper, glycoprotein 1b, alpha polypeptide antikoerper, GP1BA antikoerper, Gp1ba antikoerper
- Hintergrund
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Description: Glycoprotein Ib (GP Ib) is a platelet surface membrane glycoprotein composed of a heterodimer, an alpha chain and a beta chain, that is linked by disulfide bonds. The Gp Ib functions as a receptor for von Willebrand factor (VWF). The complete receptor complex includes noncovalent association of the alpha and beta subunits with platelet glycoprotein IX and platelet glycoprotein V. The binding of the GP Ib-IX-V complex to VWF facilitates initial platelet adhesion to vascular subendothelium after vascular injury, and also initiates signaling events within the platelet that lead to enhanced platelet activation, thrombosis, and hemostasis. This gene encodes the alpha subunit. Mutations in this gene result in Bernard-Soulier syndromes and platelet-type von Willebrand disease. The coding region of this gene is known to contain a polymophic variable number tandem repeat (VNTR) domain that is associated with susceptibility to nonarteritic anterior ischemic optic neuropathy.
Aliases: GP1BA, BSS, GP1B, VWDP, GPIbA, BDPLT1, BDPLT3, DBPLT3, GPIbalpha, CD42b-alpha
- Molekulargewicht
- 71.5 kDa
- Gen-ID
- 2811
- HGNC
- 2811
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