FCAR Antikörper (AA 22-227)
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- Target Alle FCAR Antikörper anzeigen
- FCAR (Fc Fragment of IgA, Receptor For (FCAR))
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Bindungsspezifität
- AA 22-227
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Reaktivität
- Human
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Wirt
- Maus
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Klonalität
- Monoklonal
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Konjugat
- Dieser FCAR Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), ELISA, Flow Cytometry (FACS), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Neutralization (Neut)
- Aufreinigung
- purified
- Immunogen
- Purified recombinant fragment of human CD89 (AA: extra 22-227) expressed in E. coli.
- Klon
- 2F9E10
- Isotyp
- IgG1
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- Applikationshinweise
- ELISA: 1:10000, WB: 1:500 - 1:2000, ICC: N/A, FCM: 1:200 - 1:400, IHC: N/A
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
- Purified antibody in PBS with 0.05 % sodium azide
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C/-20 °C
- Informationen zur Lagerung
- 4°C, -20°C for long term storage
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- Target
- FCAR (Fc Fragment of IgA, Receptor For (FCAR))
- Andere Bezeichnung
- CD89 (FCAR Produkte)
- Synonyme
- CD89 antikoerper, Fc fragment of IgA receptor antikoerper, Fc fragment of IgA, receptor for antikoerper, FCAR antikoerper
- Hintergrund
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Description: This gene is a member of the immunoglobulin gene superfamily and encodes a receptor for the Fc region of IgA. The receptor is a transmembrane glycoprotein present on the surface of myeloid lineage cells such as neutrophils, monocytes, macrophages, and eosinophils, where it mediates immunologic responses to pathogens. It interacts with IgA-opsonized targets and triggers several immunologic defense processes, including phagocytosis, antibody-dependent cell-mediated cytotoxicity, and stimulation of the release of inflammatory mediators. Multiple alternatively spliced transcript variants encoding different isoforms have been described for this gene.
Aliases: FCAR, FcalphaRI, CTB-61M7.2
- Molekulargewicht
- 32.3 kDa
- Gen-ID
- 2204
- HGNC
- 2204
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