Tamalin/GRASP Antikörper (AA 814-818)

Produktnummer ABIN5689207

Produktdetails anti-Tamalin/GRASP Antikörper

Target: Tamalin/GRASP (GRASP) (GRP1 (General Receptor For phosphoinositides 1)-Associated Scaffold Protein (GRASP))

Bindungsspezifität: AA 814-818

Reaktivität: Maus, Ratte, Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Tamalin/GRASP Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Spezifität: This antibody detects endogenous level of total GRASP protein.

Aufreinigung: Antibodies were purified by affinity-chromatography using epitope-specific peptide

Immunogen: GRASP antibody was raised against a peptide sequence around aa. 814-818 (Q-E-I-V-R ) derived from Rat GRASP.

Anwendungsinformationen

Applikationshinweise: Western Blot: 1:500~1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+),  pH 7.4, 150  mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store antibody at -20°C for up to one year.

Details zu Tamalin/GRASP

Target: Tamalin/GRASP (GRASP) (GRP1 (General Receptor For phosphoinositides 1)-Associated Scaffold Protein (GRASP))

Andere Bezeichnung: GRASP (GRASP Produkte)

Synonyme: GRASP antikoerper, tamalin antikoerper, TAMALIN antikoerper, general receptor for phosphoinositides 1 associated scaffold protein antikoerper, GRP1 (general receptor for phosphoinositides 1)-associated scaffold protein antikoerper, GRASP antikoerper, grasp antikoerper, Grasp antikoerper

Hintergrund: GRASP (GRP1-associated scaffold protein, tamalin) is a 395 amino acid proteinencoded by the human gene GRASP . GRASP is a scaffold protein that com-prises multiple protein-interacting domains, including a 95 kDa postsynapticdensity protein (PSD-95)/discs-large/ZO-1 (PDZ) domain, a leucine-zipperregion and a carboxyl-terminal PDZ-binding motif. GRASP is involved withintracellular trafficking and contributes to the macromolecular organizationof group 1 metabotropic glutamate receptors (mGluRs) at synapses. GRASPforms a heteromer composed of GRASP , PSCD2 and at least one mGluR-1. Italso interacts with PSCD3, mGluR-2, mGluR-3 and mGluR-5. GRASP is highlyexpressed in brain and has lower levels of expression in lung, heart, embryo, kidney and ovary.

Molekulargewicht: 95 kDa

Gen-ID: 56850

NCBI Accession: NP_064522

UniProt: Q9JHZ4