HDAC4/HDAC5/HDAC9 Antikörper

Produktnummer ABIN5689239

Produktdetails anti-HDAC4/HDAC5/HDAC9 Antikörper

Target: HDAC4/HDAC5/HDAC9 (HDAC4,HDAC5,HDAC9)

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser HDAC4/HDAC5/HDAC9 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Spezifität: This antibody detects endogenous level of total HDAC4/HDAC5/HDAC9 protein.

Aufreinigung: Antibodies were purified by affinity-chromatography using epitope-specific peptide.

Immunogen: HDAC4/HDAC5/HDAC9 (Ab-246/259/220) antibody was raised against a peptide sequence around aa.244~248/257~261/218~222 (T-A-S-E-P) derived from Human HDAC4/HDAC5/HDAC9.

Anwendungsinformationen

Applikationshinweise: Western Blot: 1:500~1:1000, Immunohistochemistry: 1:50~1:100, Immunofluorescence: 1:100~1:200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+),  pH 7.4, 150  mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store antibody at -20°C for up to one year.

Details zu HDAC4/HDAC5/HDAC9

Target: HDAC4/HDAC5/HDAC9 (HDAC4,HDAC5,HDAC9)

Andere Bezeichnung: HDAC4 / HDAC5 / HDAC9 (HDAC4/HDAC5/HDAC9 Produkte)

Hintergrund: Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. Involved in muscle maturation via its interaction with the myocyte enhancer factors such as MEF2A, MEF2C and MEF2D.

Molekulargewicht: 140, 124 kDa

Gen-ID: 9759, 10014, 9734

NCBI Accession: NP_006028, NP_001015053, NP_055522

UniProt: P56524, Q9UQL6, Q9UKV0