TWIST2 Antikörper (AA 26-30)

Produktnummer ABIN5689370

Produktdetails anti-TWIST2 Antikörper

Target: TWIST2 (Twist Homolog 2 (TWIST2))

Bindungsspezifität: AA 26-30

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TWIST2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Spezifität: This antibody detects endogenous level of total Twist2 protein.

Aufreinigung: Antibodies were purified by affinity-chromatography using epitope-specific peptide.

Immunogen: Twist2 antibody was raised against a peptide sequence around aa.26~30 (P-K-R-F-G) derived from Human Twist2.

Anwendungsinformationen

Applikationshinweise: Western Blot: 1:500~1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+),  pH 7.4, 150  mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store antibody at -20°C for up to one year.

Details zu TWIST2

Target: TWIST2 (Twist Homolog 2 (TWIST2))

Andere Bezeichnung: Twist2 (TWIST2 Produkte)

Synonyme: TWIST2 antikoerper, DERMO1 antikoerper, FFDD3 antikoerper, SETLSS antikoerper, bHLHa39 antikoerper, Dermo1 antikoerper, CDERMO-1 antikoerper, twist family bHLH transcription factor 2 antikoerper, twist basic helix-loop-helix transcription factor 2 antikoerper, TWIST2 antikoerper, Twist2 antikoerper

Hintergrund: Binds to the E-box consensus sequence 5'-CANNTG-3' as a heterodimer and inhibits transcriptional activation by MYOD1, MYOG, MEF2A and MEF2C. Also represses expression of proinflammatory cytokines such as TNFA and IL1B. Involved in postnatal glycogen storage and energy metabolism. Inhibits the premature or ectopic differentiation of preosteoblast cells during osteogenesis, possibly by changing the internal signal transduction response of osteoblasts to external growth factors.

Molekulargewicht: 18 kDa

Gen-ID: 117581

NCBI Accession: NP_476527

UniProt: Q8WVJ9

Pathways: Chromatin Binding