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BimEL Antikörper (AA 20-70)
Reaktivität: Ratte, Human, Maus
WB, ELISA, ICC, IF
Wirt: Kaninchen
Polyclonal
unconjugated
Produktnummer ABIN5689905
Produktdetails anti-BimEL Antikörper
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Target
Alle BimEL Produkte
BimEL
Bindungsspezifität
Alle Epitope für BimEL Antikörper
AA 20-70
Reaktivität
Ratte, Human, Maus
Wirt
Alle Wirte für BimEL Antikörper
Kaninchen
Klonalität
Alle Klonalitäten für BimEL Antikörper
Polyklonal
Konjugat
Alle Konjugate für BimEL Antikörper
Dieser BimEL Antikörper ist unkonjugiert
Applikation
Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Immunofluorescence (IF)
Spezifität
Bim EL antibody is human and mouse reactive. Multiple isoforms of Bim are known to exist, this antibody only detects the Bim EL isoform.
Aufreinigung
Bim EL Antibody is affinity chromatography purified via peptide column.
Immunogen
Bim EL antibody was raised against a peptide corresponding to 15 amino acids near the amino terminus of human Bim. The immunogen is located within amino acids 20 - 70 of Bim EL.
Isotyp
IgG
Alternativen
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Anwendungsinformationen
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Applikationshinweise
Bim EL antibody can be used for detection of Bim EL by Western blot at 1 - 2 μ,g/mL.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Handhabung
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Format
Liquid
Konzentration
1 mg/mL
Buffer
Bim EL Antibody is supplied in PBS containing 0.02 % sodium azide.
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung
4 °C,-20 °C
Informationen zur Lagerung
Bim EL antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
Details zu BimEL
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Target
BimEL
Andere Bezeichnung
Bim EL (BimEL Produkte )
Hintergrund
Bim EL Antibody: Members in the Bcl-2 family are critical regulators of apoptosis by either inhibiting or promoting cell death. Bcl-2 homology 3 (BH3) domain is a potent death domain. BH3 domain containing pro-apoptotic proteins, including Bad, Bax, Bid, Bik, and Hrk, form a growing subclass of the Bcl-2 family. Bim, also known as Bcl-2-like protein 11, is a pro-apoptotic member of this family and interacts with diverse members in the pro-survival Bcl-2 sub-family including Bcl-2, Bcl-xL and Bcl-w. Multiple isoforms of Bim are known to exist, with Bim EL being the longest isoform (1,2).
Molekulargewicht
Predicted: 22 kDa Observed: 24 kDa
Gen-ID
10018
NCBI Accession
NP_619527
UniProt
O43521
Zuletzt angesehen
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