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BimEL Antikörper (AA 20-70)

Reaktivität: Ratte, Human, Maus WB, ELISA, ICC, IF Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN5689905
  • Target Alle BimEL Produkte
    BimEL
    Bindungsspezifität
    • 1
    • 1
    • 1
    AA 20-70
    Reaktivität
    Ratte, Human, Maus
    Wirt
    • 2
    Kaninchen
    Klonalität
    • 2
    Polyklonal
    Konjugat
    • 2
    Dieser BimEL Antikörper ist unkonjugiert
    Applikation
    Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Immunofluorescence (IF)
    Spezifität
    Bim EL antibody is human and mouse reactive. Multiple isoforms of Bim are known to exist, this antibody only detects the Bim EL isoform.
    Aufreinigung
    Bim EL Antibody is affinity chromatography purified via peptide column.
    Immunogen
    Bim EL antibody was raised against a peptide corresponding to 15 amino acids near the amino terminus of human Bim.

    The immunogen is located within amino acids 20 - 70 of Bim EL.
    Isotyp
    IgG
  • Applikationshinweise
    Bim EL antibody can be used for detection of Bim EL by Western blot at 1 - 2 μ,g/mL.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 mg/mL
    Buffer
    Bim EL Antibody is supplied in PBS containing 0.02 % sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Bim EL antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
  • Target
    BimEL
    Andere Bezeichnung
    Bim EL (BimEL Produkte)
    Hintergrund
    Bim EL Antibody: Members in the Bcl-2 family are critical regulators of apoptosis by either inhibiting or promoting cell death. Bcl-2 homology 3 (BH3) domain is a potent death domain. BH3 domain containing pro-apoptotic proteins, including Bad, Bax, Bid, Bik, and Hrk, form a growing subclass of the Bcl-2 family. Bim, also known as Bcl-2-like protein 11, is a pro-apoptotic member of this family and interacts with diverse members in the pro-survival Bcl-2 sub-family including Bcl-2, Bcl-xL and Bcl-w. Multiple isoforms of Bim are known to exist, with Bim EL being the longest isoform (1,2).
    Molekulargewicht
    Predicted: 22 kDa

    Observed: 24 kDa
    Gen-ID
    10018
    NCBI Accession
    NP_619527
    UniProt
    O43521
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