SKIV2L Antikörper (AA 260-310)

Produktnummer ABIN5689978

Produktdetails anti-SKIV2L Antikörper

Target: SKIV2L (Superkiller Viralicidic Activity 2-Like (SKIV2L))

Bindungsspezifität: AA 260-310

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SKIV2L Antikörper ist unkonjugiert

Applikation: ELISA, Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Spezifität: GPRASP1 antibody is human and mouse reactive. This antibody is predicted to not cross-react with GPRASP2.

Aufreinigung: GPRASP1 antibody is affinity chromatography purified via peptide column.

Immunogen: GPRASP1 antibody was raised against a 15 amino acid peptide near the amino terminus of human GPRASP1.

The immunogen is located within amino acids 260 - 310 of GPRASP1.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: GPRASP1 antibody can be used for detection of GPRASP1 by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: GPRASP1 antibody is supplied in PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: GPRASP1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.

Details zu SKIV2L

Target: SKIV2L (Superkiller Viralicidic Activity 2-Like (SKIV2L))

Andere Bezeichnung: SKI2W (SKIV2L Produkte)

Hintergrund: The G protein-coupled receptor associated sorting protein 1 (GPRASP1) is a member of the GPRASP family and is thought to modulate lysosomal sorting and functional down-regulation of a variety of G-protein coupled receptors (1,2). GPRASP1 interacts with receptors such as the D2 dopamine receptor (DRD2), delta opioid receptor (OPRD1), beta-2 adrenergic receptor (ADRB2), D4 dopamine receptor (DRD4) and cannabinoid 1 receptor (CNR1) and targets these proteins for degradation in lysosomes (2). Recently, it has been shown that increased GPRASP1 levels may act as a potential biomarker for breast cancer (3).

Molekulargewicht: Predicted: 153 kDa

Observed: 150 kDa

Gen-ID: 9737

NCBI Accession: NP_001171656

UniProt: Q5JY77