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PHC3 Antikörper (AA 240-290)

PHC3 Reaktivität: Human, Maus, Ratte WB, ELISA Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN5690097
  • Target Alle PHC3 Antikörper anzeigen
    PHC3 (Polyhomeotic Homolog 3 (PHC3))
    Bindungsspezifität
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 240-290
    Reaktivität
    • 22
    • 13
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Human, Maus, Ratte
    Wirt
    • 21
    • 1
    Kaninchen
    Klonalität
    • 22
    Polyklonal
    Konjugat
    • 15
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser PHC3 Antikörper ist unkonjugiert
    Applikation
    • 11
    • 6
    • 4
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA
    Spezifität
    PHC3 antibody is human, mouse and rat specific. At least six isoforms of PHC3 are known to exist.
    Aufreinigung
    PHC3 antibody is affinity chromatography purified via peptide column.
    Immunogen
    PHC3 antibody was raised against a 19 amino acid peptide near the amino terminus of human PHC3.

    The immunogen is located within amino acids 240 - 290 of PHC3.
    Isotyp
    IgG
    Top Product
    Discover our top product PHC3 Primärantikörper
  • Applikationshinweise
    PHC3 antibody can be used for detection of PHC3 by Western blot at 1 - 2 μ,g/mL.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 mg/mL
    Buffer
    PHC3 antibody is supplied in PBS containing 0.02 % sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    PHC3 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
  • Target
    PHC3 (Polyhomeotic Homolog 3 (PHC3))
    Andere Bezeichnung
    PHC3 (PHC3 Produkte)
    Synonyme
    EDR3 antikoerper, HPH3 antikoerper, E030046K01Rik antikoerper, Edr3 antikoerper, Hph3 antikoerper, polyhomeotic homolog 3 antikoerper, polyhomeotic-like 3 (Drosophila) antikoerper, Phc3 antikoerper, PHC3 antikoerper
    Hintergrund
    Polycomb group (PcG) proteins assemble into multimeric protein complexes, which are involved in maintaining the transcriptional repressive state of genes throughout development (1). PHC3 (Polyhomeotic-like protein 3), also known as Early development regulatory protein 3, is a 983 amino acid nuclear protein that is a component of the PcG multiprotein PRC1 complex (2). PRC1 complex acts via chromatin remodeling and modification of histones. PHC3 contains 1 FCS-type zinc finger and SAM (sterile alpha motif) domain (2-3). PHC 3 has been regarded as a candidate tumor suppressor of osteosarcoma (4).
    Molekulargewicht
    Predicted: 109 kDa

    Observed: 120 kDa
    Gen-ID
    80012
    NCBI Accession
    NP_079223
    UniProt
    Q8NDX5
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