SPIB Antikörper (AA 200-250)
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- Target Alle SPIB Antikörper anzeigen
- SPIB (Spi-B Transcription Factor (Spi-1/PU.1 Related) (SPIB))
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Bindungsspezifität
- AA 200-250
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Reaktivität
- Human, Maus, Ratte
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser SPIB Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Spezifität
- SPIB antibody is human, mouse and rat reactive. At least four isoforms of SPIB are known to exist, this antibody will detect all but isoform 3.
- Aufreinigung
- SPIB antibody is affinity chromatography purified via peptide column.
- Immunogen
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SPIB antibody was raised against a 17 amino acid peptide near the carboxy terminus of human SPIB.
The immunogen is located within amino acids 200 - 250 of SPIB. - Isotyp
- IgG
- Top Product
- Discover our top product SPIB Primärantikörper
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- Applikationshinweise
- SPIB antibody can be used for detection of SPIB by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 2.5 μ,g/mL.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 mg/mL
- Buffer
- SPIB antibody is supplied in PBS containing 0.02 % sodium azide.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C,-20 °C
- Informationen zur Lagerung
- SPIB antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
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- Target
- SPIB (Spi-B Transcription Factor (Spi-1/PU.1 Related) (SPIB))
- Andere Bezeichnung
- SPIB (SPIB Produkte)
- Synonyme
- spi-b antikoerper, spib antikoerper, spiba antikoerper, SPI-B antikoerper, B42b-like antikoerper, Spi-B antikoerper, Spi-B transcription factor L homeolog antikoerper, Spi-B transcription factor antikoerper, Spi-B transcription factor (Spi-1/PU.1 related) antikoerper, spib.L antikoerper, SPIB antikoerper, Spib antikoerper
- Hintergrund
- SPIB is a member of the ETS transcription factor family that influences lymphoid development and activity and binds the consensus DNA site GGA (A/T) through a unique winged helix-turn-helix motif known as the ETS domain (1). SPIB is found in hematopoietic cells such as B cells and plasmacytoid dendritic cells (DC) (2,3). It promotes the development of plasmacytoid dendritic cells (pDCs) or natural interferon (IFN)-producing cells. SPIB may be required for B-cell receptor (BCR) signaling, which is necessary for normal B-cell development and antigenic stimulation (3,4).
- Molekulargewicht
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Predicted: 19, 25, 29 kDa
Observed: 20 kDa - Gen-ID
- 6689
- NCBI Accession
- NP_003112
- UniProt
- Q01892
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