WAPAL Antikörper (AA 30-80)

Produktnummer ABIN5690322

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch WAPAL in ELISA, WB, IF und IHC (p). Er zeigt eine Reaktivität gegenüber Human, Maus und Ratte.

Kurzübersicht für WAPAL Antikörper (AA 30-80) (ABIN5690322)

Target: WAPAL (Wings Apart-Like Protein Homolog (WAPAL))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser WAPAL Antikörper ist unkonjugiert

Applikation: ELISA, Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-WAPAL Antikörper

Bindungsspezifität: AA 30-80

Spezifität: WAPL antibody is human, mouse and rat reactive. At least four isoforms of WAPL are known to exist.

Aufreinigung: WAPL antibody is affinity chromatography purified via peptide column.

Immunogen: WAPL antibody was raised against an 18 amino acid peptide near the amino terminus of human WAPL.

The immunogen is located within amino acids 30 - 80 of WAPL.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WAPL antibody can be used for detection of WAPL by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for Immunohistochemistry at 5 μ,g/mL. For Immunoflorescence start at 20 μ,g/mL.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: WAPL antibody is supplied in PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: WAPL antibody can be stored at 4°C for three months and -20°C, stable for up to one year.

Details zu WAPAL

Target: WAPAL (Wings Apart-Like Protein Homolog (WAPAL))

Andere Bezeichnung: WAPL

Hintergrund: WAPL (wings apart-like), also known as WAPAL or FOE, is a 1,190 amino acid protein that contains one WAPL domain and may play an important role in cell growth (1). It is expressed in an isoform dependent manner in heart, skeletal muscle (isoform 2) and uterine cervix tumor tissue (isoform 1) (1,2,4). WAPL is involved in sister-chromatid adhesion and promotes release of cohesin from chromosomes by directly interacting with its regulatory subunits (3,4). WAPL is a new regulator of the development and metastasis of cancerous tissue (4,5).

Molekulargewicht: Predicted: 131 kDa

Observed: 140 kDa

Gen-ID: 23063

NCBI Accession: NP_055860

UniProt: Q7Z5K2

Pathways: Chromatin Binding