ZAK Antikörper (AA 276-511)
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- Target Alle ZAK Antikörper anzeigen
- ZAK (Mitogen-Activated Protein Kinase Kinase Kinase MLT (ZAK))
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Bindungsspezifität
- AA 276-511
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Reaktivität
- Human, Maus, Ratte
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser ZAK Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), ELISA
- Marke
- Picoband™
- Kreuzreaktivität (Details)
- No cross reactivity with other proteins.
- Produktmerkmale
- Rabbit IgG polyclonal antibody for MAP3K20 detection. Tested with WB, Direct ELISA in Human,Mouse,Rat.
- Immunogen
- E. coli-derived human MAP3K20 recombinant protein (Position: F276-E511).
- Top Product
- Discover our top product ZAK Primärantikörper
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- Applikationshinweise
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Recommended Detection Systems: Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ABIN921124) for Western blot.
Application Details: Western blot, 0.1-0.5 μg/mL
Direct ELISA, 0.1-0.5 μg/mL - Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Lyophilized
- Rekonstitution
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
- Buffer
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg NaN3.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C,-20 °C
- Informationen zur Lagerung
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At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for a longer time. Avoid repeated freezing and thawing.
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- Target
- ZAK (Mitogen-Activated Protein Kinase Kinase Kinase MLT (ZAK))
- Andere Bezeichnung
- MAP3K20 (ZAK Produkte)
- Synonyme
- MLTK antikoerper, RGD1561394 antikoerper, AZK antikoerper, MLK7 antikoerper, MLT antikoerper, MRK antikoerper, mlklak antikoerper, pk antikoerper, AV006891 antikoerper, B230120H23Rik antikoerper, MLTKalpha antikoerper, MLTKbeta antikoerper, mitogen-activated protein kinase kinase kinase 20 antikoerper, Map3k20 antikoerper, MAP3K20 antikoerper
- Hintergrund
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Synonyms: Mitogen-activated protein kinase kinase kinase 20
Tissue Specificity: Ubiquitously expressed. Isoform 2 is the predominant form in all tissues examined, except for liver, in which isoform 1 is more highly expressed.
Background: Sterile alpha motif and leucine zipper containing kinase AZK, also known as ZAK, is a human gene. This gene is a member of the MAPKKK family of signal transduction molecules and encodes a protein with an N-terminal kinase catalytic domain, followed by a leucine zipper motif and a sterile-alpha motif (SAM). This magnesium-binding protein forms homodimers and is located in the cytoplasm. The protein mediates gamma radiation signaling leading to cell cycle arrest and activity of this protein plays a role in cell cycle checkpoint regulation in cells. The protein also has pro-apoptotic activity. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
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