PRDM1 Antikörper (AA 1-230)

Produktnummer ABIN5692915

Produktdetails anti-PRDM1 Antikörper

Target: PRDM1 (PR Domain Containing 1, with ZNF Domain (PRDM1))

Bindungsspezifität: AA 1-230

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PRDM1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Marke: Picoband™

Kreuzreaktivität (Details): No cross reactivity with other proteins.

Produktmerkmale: Rabbit IgG polyclonal antibody for PRDM1/Blimp1 detection. Tested with WB, IHC-P, Direct ELISA in Human,Mouse,Rat.

Immunogen: E. coli-derived human PRDM1/Blimp1 recombinant protein (Position: M1-Q230).

Anwendungsinformationen

Applikationshinweise:

Recommended Detection Systems: Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ABIN921124) for Western blot.

Application Details: Western blot, 0.1-0.5 μg/mL
Immunohistochemistry(Paraffin-embedded Section), 0.5-1 μg/mL
Direct ELISA, 0.1-0.5 μg/mL

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na₂HPO₄, 0.05 mg NaN₃.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for a longer time. Avoid repeated freezing and thawing.

Details zu PRDM1

Target: PRDM1 (PR Domain Containing 1, with ZNF Domain (PRDM1))

Andere Bezeichnung: PRDM1 (PRDM1 Produkte)

Synonyme: GB11750 antikoerper, CG5249 antikoerper, Dmel\\CG5249 antikoerper, blimp-1 antikoerper, dBlimp-1 antikoerper, dBlimp1 antikoerper, Blimp-1 antikoerper, Blimp1 antikoerper, nrd antikoerper, prdm1 antikoerper, ubo antikoerper, wu:fb99c12 antikoerper, zgc:91885 antikoerper, MGC52536 antikoerper, PRDM1 antikoerper, blimp1 antikoerper, xblimp1 antikoerper, prdi-bf1 antikoerper, BLIMP1 antikoerper, PRDI-BF1 antikoerper, ZNFPR1A1 antikoerper, PR/SET domain 1 antikoerper, probable serine/threonine-protein kinase DDB_G0282963 antikoerper, CG5249 gene product from transcript CG5249-RF antikoerper, blimp-1 antikoerper, PR domain containing 1a, with ZNF domain antikoerper, PR domain 1 S homeolog antikoerper, B lymphocyte induced maturation protein 1 antikoerper, PR domain 1 antikoerper, PR domain containing 1, with ZNF domain antikoerper, PRDM1 antikoerper, LOC408295 antikoerper, Blimp-1 antikoerper, CpipJ_CPIJ007425 antikoerper, prdm1a antikoerper, prdm1.S antikoerper, prdm1 antikoerper, Prdm1 antikoerper

Hintergrund:

Synonyms: PR domain zinc finger protein 1, BLIMP-1, Beta-interferon gene positive regulatory domain I-binding factor, PR domain-containing protein 1, Positive regulatory domain I-binding factor 1, PRDI-BF1, PRDI-binding factor 1, PRDM1, BLIMP1

Background: PR domain zinc finger protein 1 also known as BLIMP-1 is a protein that in humans is encoded by the PRDM1 gene. This gene encodes a protein that acts as a repressor of beta-interferon gene expression. The protein binds specifically to the PRDI (positive regulatory domain I element) of the beta-IFN gene promoter. Transcription of this gene increases upon virus induction. Two alternatively spliced transcript variants that encode different isoforms have been reported.

UniProt: O75626

Pathways: Regulation of Muscle Cell Differentiation