SPR Antikörper (AA 36-261)

Produktnummer ABIN5692972

Produktdetails anti-SPR Antikörper

Target: SPR (Sepiapterin Reductase (SPR))

Bindungsspezifität: AA 36-261

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SPR Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Marke: Picoband™

Kreuzreaktivität (Details): No cross reactivity with other proteins.

Produktmerkmale: Rabbit IgG polyclonal antibody for SPR detection. Tested with WB, Direct ELISA in Human,Mouse.

Immunogen: E. coli-derived human SPR recombinant protein (Position: V36-K261).

Anwendungsinformationen

Applikationshinweise:

Recommended Detection Systems: Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ABIN921124) for Western blot.

Application Details: Western blot,0.1-0.5 μg/mL
Direct ELISA,0.1-0.5 μg/mL

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na₂HPO₄, 0.05 mg NaN₃.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for a longer time. Avoid repeated freezing and thawing.

Referenzen für anti-SPR Antikörper (ABIN5692972)

Hu, Wang, Rao, Zhao, Yang, Hu, He, Xia, Liu, Zhen, Di, Xie, Xia, Zhu: "Alterations in the endometrium of rats, rabbits, and Macaca mulatta that received an implantation of copper/low-density polyethylene nanocomposite." in: International journal of nanomedicine, Vol. 9, pp. 1127-38, (2015) (PubMed).

Details zu SPR

Target: SPR (Sepiapterin Reductase (SPR))

Andere Bezeichnung: SPR (SPR Produkte)

Synonyme: SDR38C1 antikoerper, AA409688 antikoerper, ENSMUSG00000071345 antikoerper, Gm10328 antikoerper, CG12117 antikoerper, Dmel\\CG12117 antikoerper, SR antikoerper, sptr antikoerper, xspr antikoerper, DDBDRAFT_0188686 antikoerper, DDBDRAFT_0191275 antikoerper, DDB_0188686 antikoerper, DDB_0191275 antikoerper, zgc:194446 antikoerper, sepiapterin reductase antikoerper, Sepiapterin reductase antikoerper, sepiapterin reductase L homeolog antikoerper, sepiapterin reductase b antikoerper, SPR antikoerper, Spr antikoerper, Sptr antikoerper, spr.L antikoerper, sprE antikoerper, CpipJ_CPIJ000511 antikoerper, sr antikoerper, spr antikoerper, sprb antikoerper

Hintergrund:

Synonyms: Sepiapterin reductase, SPR, SPR

Background: Sepiapterin reductase is an enzyme that in humans is encoded by the SPR gene. This gene encodes an aldo-keto reductase that catalyzes the NADPH-dependent reduction of pteridine derivatives and is important in the biosynthesis of tetrahydrobiopterin (BH4). Mutations in this gene result in DOPA-responsive dystonia due to sepiaterin reductase deficiency. A pseudogene has been identified on chromosome 1.

UniProt: P35270

Pathways: Regulation of Systemic Arterial Blood Pressure by Hormones, Feeding Behaviour, Smooth Muscle Cell Migration