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POLR2A/RPB1 Antikörper (AA 1148-1384)

POLR2A Reaktivität: Human, Maus, Ratte IHC, ELISA Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN5693106
  • Target Alle POLR2A/RPB1 (POLR2A) Antikörper anzeigen
    POLR2A/RPB1 (POLR2A) (RNA Polymerase II Subunit RPB1 (POLR2A))
    Bindungsspezifität
    • 17
    • 16
    • 11
    • 7
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1148-1384
    Reaktivität
    • 88
    • 46
    • 38
    • 6
    • 6
    • 6
    • 5
    • 5
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    Human, Maus, Ratte
    Wirt
    • 71
    • 17
    • 1
    • 1
    • 1
    Kaninchen
    Klonalität
    • 55
    • 36
    Polyklonal
    Konjugat
    • 53
    • 6
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 1
    • 1
    Dieser POLR2A/RPB1 Antikörper ist unkonjugiert
    Applikation
    • 49
    • 26
    • 23
    • 20
    • 12
    • 10
    • 8
    • 7
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Immunohistochemistry (IHC), ELISA
    Kreuzreaktivität (Details)
    No cross reactivity with other proteins.
    Produktmerkmale
    Rabbit IgG polyclonal antibody for POLR2A detection. Tested with IHC-P, Direct ELISA in Human,Mouse,Rat.
    Immunogen
    E. coli-derived human POLR2A recombinant protein (Position: A1148-H1384).
    Top Product
    Discover our top product POLR2A Primärantikörper
  • Applikationshinweise

    Recommended Detection Systems: HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (SV0002-1) for IHC(P).

    Application Details: Immunohistochemistry(Paraffin-embedded Section), 0.5-1 μg/mL
    Direct ELISA, 0.1-0.5 μg/mL

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Rekonstitution
    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
    Buffer
    Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg NaN3.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    At -20°C for one year. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for a longer time. Avoid repeated freezing and thawing.
  • Target
    POLR2A/RPB1 (POLR2A) (RNA Polymerase II Subunit RPB1 (POLR2A))
    Andere Bezeichnung
    POLR2A (POLR2A Produkte)
    Synonyme
    NCU02103.1 antikoerper, 19.m02399 antikoerper, POLR2A antikoerper, 220kDa antikoerper, Rpb1 antikoerper, Rpo2-1 antikoerper, POLR2 antikoerper, POLRA antikoerper, RPB1 antikoerper, RPBh1 antikoerper, RPO2 antikoerper, RPOL2 antikoerper, RpIILS antikoerper, hRPB220 antikoerper, hsRPB1 antikoerper, DNA-directed RNA polymerase II largest subunit antikoerper, DNA-directed RNA polymerase II subunit RPB1 antikoerper, RNA polymerase II large subunit Rpb1 antikoerper, RNA polymerase II subunit A antikoerper, DNA-directed RNA polymerase II largest subunit, putative antikoerper, polymerase (RNA) II (DNA directed) polypeptide A, 220kDa antikoerper, polymerase (RNA) II (DNA directed) polypeptide A antikoerper, NCU02103 antikoerper, BBOV_I003360 antikoerper, EDI_169920 antikoerper, CMU_000800 antikoerper, SJAG_01713 antikoerper, MGYG_01527 antikoerper, POLR2A antikoerper, TP03_0185 antikoerper, EBI_22514 antikoerper, CGB_E5020W antikoerper, polr2a antikoerper, Polr2a antikoerper
    Hintergrund

    Synonyms: DNA-directed RNA polymerase II subunit RPB1, RNA polymerase II subunit B1, DNA-directed RNA polymerase II subunit A, DNA-directed RNA polymerase III largest subunit, RNA-directed RNA polymerase II subunit RPB1, POLR2A, POLR2

    Background: DNA-directed RNA polymerase II subunit RPB1, also known as RPB1, is an enzyme that in humans is encoded by the POLR2A gene. This gene encodes the largest subunit of RNA polymerase II, the polymerase responsible for synthesizing messenger RNA in eukaryotes. The product of this gene contains a carboxy terminal domain composed of heptapeptide repeats that are essential for polymerase activity. These repeats contain serine and threonine residues that are phosphorylated in actively transcribing RNA polymerase. In addition, this subunit, in combination with several other polymerase subunits, forms the DNA binding domain of the polymerase, a groove in which the DNA template is transcribed into RNA.

    UniProt
    P24928
    Pathways
    Regulatorische RNA Pathways
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