PCBP1 Antikörper (Internal Region)
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- Target Alle PCBP1 Antikörper anzeigen
- PCBP1 (Poly(rC) Binding Protein 1 (PCBP1))
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Bindungsspezifität
- AA 234-247, Internal Region
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Reaktivität
- Human, Maus, Ratte, Hund
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Wirt
- Ziege
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Klonalität
- Polyklonal
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Konjugat
- Dieser PCBP1 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Enzyme Immunoassay (EIA)
- Sequenz
- C-ADLAKLNQVA RQQSH
- Spezifität
- Recognizes PCBP1 (234-247).
- Kreuzreaktivität (Details)
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Species reactivity (expected):Mouse, Rat, Canine (Dog).
Species reactivity (tested):Human. - Aufreinigung
- Ammonium Sulphate Precipitation followed by antigen Affinity Chromatography using the immunizing peptide
- Immunogen
- Peptide with sequence from the internal region of the protein sequence according to NP_006187.2. Genename: PCBP1
- Top Product
- Discover our top product PCBP1 Primärantikörper
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- Applikationshinweise
- Optimal working dilution should be determined by the investigator.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Konzentration
- 0.5 mg/mL
- Buffer
- Tris saline, pH ~7.3 with 0.02 % Sodium Azide and 0.5 % BSA
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freezing and thawing.
- Lagerung
- 4 °C/-20 °C
- Informationen zur Lagerung
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- Target
- PCBP1 (Poly(rC) Binding Protein 1 (PCBP1))
- Andere Bezeichnung
- PCBP1 (PCBP1 Produkte)
- Synonyme
- PCBP1 antikoerper, HNRPE1 antikoerper, HNRPX antikoerper, hnRNP-E1 antikoerper, hnRNP-X antikoerper, hnRNP E1 antikoerper, WBP17 antikoerper, [a]CP-1 antikoerper, alphaCP-1 antikoerper, RGD1561319 antikoerper, poly(rC) binding protein 1 antikoerper, poly(rC) binding protein 1 L homeolog antikoerper, poly(rC)-binding protein 1 antikoerper, PCBP1 antikoerper, pcbp1.L antikoerper, LOC100388387 antikoerper, Pcbp1 antikoerper
- Hintergrund
- The protein encoded by this gene appears to be multifunctional. It along with PCBP-2 and hnRNPK corresponds to the major cellular poly(rC)-binding protein. It contains three K-homologous (KH) domains which may be involved in RNA binding. This encoded protein together with PCBP-2 also functions as translational coactivators of poliovirus RNA via a sequence-specific interaction with stem-loop IV of the IRES and promote poliovirus RNA replication by binding to its 5'-terminal cloverleaf structure. It has also been implicated in translational control of the 15-lipoxygenase mRNA, human Papillomavirus type 16 L2 mRNA, and hepatitis A virus RNA. The encoded protein is also suggested to play a part in formation of a sequence-specific alpha-globin mRNP complex which is associated with alpha-globin mRNA stability.Synonyms: Alpha-CP1, HNRPE1, HNRPX, Heterogeneous nuclear ribonucleoprotein E1, Nucleic acid-binding protein SUB2.3, Poly(rC)-binding protein 1, SUB2.3, hnRNP E1
- Gen-ID
- 5093
- NCBI Accession
- NP_006187
- UniProt
- Q15365
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