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SNAIL Antikörper (N-Term)
SNAI1
Reaktivität: Human, Maus, Ratte
WB, IHC (p), EIA
Wirt: Ziege
Polyclonal
unconjugated
Produktdetails anti-SNAIL Antikörper
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Target
Alle SNAIL (SNAI1) Antikörper anzeigen
SNAIL (SNAI1)
Bindungsspezifität
Alle Epitope für SNAIL Antikörper
N-Term
Reaktivität
Alle Reaktivitäten für SNAIL Antikörper
Human, Maus, Ratte
Wirt
Alle Wirte für SNAIL Antikörper
Ziege
Klonalität
Alle Klonalitäten für SNAIL Antikörper
Polyklonal
Konjugat
Alle Konjugate für SNAIL Antikörper
Dieser SNAIL Antikörper ist unkonjugiert
Applikation
Alle Applikationen für SNAIL Antikörper
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
Sequenz
RKPSDPNRKP NY-C
Spezifität
Snail homolog 1 / SNAI1
Kreuzreaktivität (Details)
Species reactivity (expected):Rat. Species reactivity (tested):Human, Mouse.
Aufreinigung
Ammonium Sulphate Precipitation followed by antigen Affinity Chromatography using the immunizing peptide
Immunogen
Peptide with sequence from the N Terminus of the protein sequence according to NP_005976.2. Genename: SNAI1
Top Product
Discover our top product SNAI1 Primärantikörper
Alternativen
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Anwendungsinformationen
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Applikationshinweise
Optimal working dilution should be determined by the investigator.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Handhabung
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Konzentration
0.5 mg/mL
Buffer
Tris saline, pH ~7.3 with 0.02 % Sodium Azide and 0.5 % BSA
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handhabung
Avoid repeated freezing and thawing.
Lagerung
4 °C/-20 °C
Informationen zur Lagerung
Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Details zu SNAIL
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Target
SNAIL (SNAI1)
Andere Bezeichnung
SNAI1 (SNAI1 Produkte )
Synonyme
SLUGH2 antikoerper, SNA antikoerper, SNAH antikoerper, SNAIL antikoerper, SNAIL1 antikoerper, dJ710H13.1 antikoerper, AI194338 antikoerper, Sna antikoerper, Sna1 antikoerper, Snail antikoerper, Snail1 antikoerper, SNAI1 antikoerper, BG:DS01845.1 antikoerper, CG3956 antikoerper, Dmel\\CG3956 antikoerper, Sco antikoerper, br28 antikoerper, br29 antikoerper, l(2)35Db antikoerper, l(2)br28 antikoerper, l(2)br29 antikoerper, l(3)br28 antikoerper, l35Db antikoerper, sn antikoerper, Xsnail antikoerper, sna antikoerper, snail1 antikoerper, xSna antikoerper, Snai antikoerper, sna2 antikoerper, snail2 antikoerper, cb643 antikoerper, sna-1 antikoerper, sna1 antikoerper, snai1 antikoerper, snail1a antikoerper, zgc:109820 antikoerper, snail family transcriptional repressor 1 antikoerper, snail family zinc finger 1 antikoerper, snail homolog 1 (Drosophila) antikoerper, snail antikoerper, zinc-finger transcription factor Snail antikoerper, snail family zinc finger 1 S homeolog antikoerper, protein escargot antikoerper, transcription factor protein antikoerper, snail zinc finger protein antikoerper, snail family zinc finger 1b antikoerper, snail family zinc finger 1a antikoerper, SNAI1 antikoerper, Snai1 antikoerper, sna antikoerper, snail antikoerper, snai1.S antikoerper, LOC410464 antikoerper, snai1b antikoerper, snai1a antikoerper
Hintergrund
Zinc finger protein SNAI1 (SNAIL) is a zinc finger transcriptional repressor which down regulates the expression of ectodermal gene within the mesoderm and thus functions to form the mesoderm and neural crest. It is reported that SNAI1 acts as an important factor of tumor invasion as evidenced by its role in E-cadherin down-regulation and induction of epithelial-mesenchymal transition (EMT). In human breast cancer, the expression of SNAI1 and/or the homologous SNAI2 (Slug) has been associated with E-cadherin repression, local or distant metastasis, tumor recurrence, or poor prognosis in different tumor series. It is also reported that Snail 1 protein in the stroma may be a new putative prognosis marker for colon tumors. In recent studies SNAI1 is found to be potential target for proteasome degradation by hypoxia-controlled FBXL14 ubiquitin ligase targets.Synonyms: Protein snail homolog 1, SNAH, Zinc finger protein SNAI1
Gen-ID
6615
NCBI Accession
NP_005976
UniProt
O95863
Pathways
Negative Regulation of intrinsic apoptotic Signaling
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