WTAP Antikörper
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- Target Alle WTAP Antikörper anzeigen
- WTAP (Wilms Tumor 1 Associated Protein (WTAP))
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Reaktivität
- Human, Maus, Ratte
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser WTAP Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), ELISA, Immunoprecipitation (IP)
- Immunogen
- Wilms tumor 1 associated protein
- Isotyp
- IgG
- Top Product
- Discover our top product WTAP Primärantikörper
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- Applikationshinweise
- WB:1:500-1:2000
- Kommentare
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Jurkat cells were subjected to SDS PAGE followed by western blot with FNab09529(WTAP antibody) at dilution of 1:1000
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Buffer
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freeze / thaw cycles.
- Lagerung
- -20 °C
- Haltbarkeit
- 12 months
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- Target
- WTAP (Wilms Tumor 1 Associated Protein (WTAP))
- Andere Bezeichnung
- WTAP (WTAP Produkte)
- Synonyme
- MGC75954 antikoerper, WTAP antikoerper, RGD1563824 antikoerper, wu:fi29a09 antikoerper, zgc:66202 antikoerper, 2810408K05Rik antikoerper, 9430038B09Rik antikoerper, WT1 associated protein antikoerper, Wilms tumor 1 associated protein antikoerper, wilms tumor 1 associated protein antikoerper, WT1 associated protein L homeolog antikoerper, Wilms tumour 1-associating protein antikoerper, wtap antikoerper, WTAP antikoerper, CpipJ_CPIJ006489 antikoerper, Wtap antikoerper, wtap.L antikoerper
- Hintergrund
- Synonyms:DKFZp686F20131, Female lethal(2)D homolog, hFL(2)D, KIAA0105, WT1 associated protein, WTAP Background:Regulatory subunit of the WMM N6-methyltransferase complex, a multiprotein complex that mediates N6-methyladenosine(m6A) methylation of some adenosine residues of some mRNAs and plays a role in the efficiency of mRNA splicing, processing and mRNA stability. Required for accumulation of METTL3 and METTL14 to nuclear speckle(PubMed:24316715, PubMed:24407421, PubMed:24981863). Acts as a mRNA splicing regulator(PubMed:12444081). Regulates G2/M cell-cycle transition by binding to the 3' UTR of CCNA2, which enhances its stability(PubMed:17088532). Impairs WT1 DNA-binding ability and inhibits expression of WT1 target genes(PubMed:17095724).
- Molekulargewicht
- 49kDa,Observed 55kDa
- Gen-ID
- 9589
- UniProt
- Q15007
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