DHX36 Antikörper
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- Target Alle DHX36 Antikörper anzeigen
- DHX36 (DEAH (Asp-Glu-Ala-His) Box Polypeptide 36 (DHX36))
- Reaktivität
- Human, Maus, Ratte
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser DHX36 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunoprecipitation (IP)
- Immunogen
- DEAH (Asp-Glu-Ala-His) box polypeptide 36
- Isotyp
- IgG
- Top Product
- Discover our top product DHX36 Primärantikörper
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- Applikationshinweise
- Optimal working dilution should be determined by the investigator.
- Kommentare
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human brain tissue were subjected to SDS PAGE followed by western blot with FNab02380(DHX36 antibody) at dilution of 1:800
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Buffer
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freeze / thaw cycles.
- Lagerung
- -20 °C
- Haltbarkeit
- 12 months
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- Target
- DHX36 (DEAH (Asp-Glu-Ala-His) Box Polypeptide 36 (DHX36))
- Andere Bezeichnung
- DHX36 (DHX36 Produkte)
- Synonyme
- DHX57 antikoerper, DDX36 antikoerper, G4R1 antikoerper, MLEL1 antikoerper, RHAU antikoerper, 2810407E23Rik antikoerper, AI452301 antikoerper, AU022184 antikoerper, Ddx36 antikoerper, mKIAA1488 antikoerper, DEAH-box helicase 36 antikoerper, ATP-dependent RNA helicase DHX36 antikoerper, DEAH (Asp-Glu-Ala-His) box polypeptide 36 antikoerper, Dhx36 antikoerper, DHX36 antikoerper, dhx36 antikoerper, LOC100456222 antikoerper, LOC100633205 antikoerper
- Hintergrund
- Synonyms:DDX36, KIAA1488, MLEL1, RHAU Background:Proposed to have a global role in regulating mRNA expression including transcriptional regulation and mRNA stability. Binds with high affinity to and resolves tetramolecular RNA and DNA quadruplex structures. Unwinds intramolecular quadruplexes derived from the ZIC1 and the MYC promoters. Binds to quadruplex structures in the promoters of YY1 and ALPL genes and regulates their expression. Binds to telomerase RNA template component(TERC) 5'-end(nucleotides 1-43) and unwinds an internal quadruplex formation in TERC 5'-end to promote P1 helix formation, the P1 helix acts as a template boundary ensuring accurate reverse transcription and is disrupted by quadruplex formation. May be involved in regulation of telomere length. Plays a role in degradation and deadenylation of mRNAs containing in their 3'-UTR the consensus ARE sequence element. May function in sex development and spermatogenesis. May play a role in ossification.
- Molekulargewicht
- 120 kDa
- Gen-ID
- 170506
- UniProt
- Q9H2U1
- Pathways
- Toll-Like Receptors Cascades
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