INSIG2 Antikörper
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- Target Alle INSIG2 Antikörper anzeigen
- INSIG2 (Insulin Induced Gene 2 (INSIG2))
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Reaktivität
- Human, Maus, Ratte
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser INSIG2 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)
- Immunogen
- insulin induced gene 2
- Isotyp
- IgG
- Top Product
- Discover our top product INSIG2 Primärantikörper
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- Applikationshinweise
- Optimal working dilution should be determined by the investigator.
- Kommentare
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rat liver tissue were subjected to SDS PAGE followed by western blot with FNab04334( INSIG2 Antibody) at dilution of 1:1000
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Buffer
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freeze / thaw cycles.
- Lagerung
- -20 °C
- Haltbarkeit
- 12 months
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- Target
- INSIG2 (Insulin Induced Gene 2 (INSIG2))
- Andere Bezeichnung
- INSIG2 (INSIG2 Produkte)
- Synonyme
- MGC82156 antikoerper, INSIG-2 antikoerper, 2900053I11Rik antikoerper, C730043J18Rik antikoerper, Insig-2 antikoerper, insulin induced gene 2 antikoerper, insulin induced gene 2 L homeolog antikoerper, insig2 antikoerper, insig2.L antikoerper, INSIG2 antikoerper, Insig2 antikoerper
- Hintergrund
- Synonyms: Background:Mediates feedback control of cholesterol synthesis by controlling SCAP and HMGCR. Functions by blocking the processing of sterol regulatory element-binding proteins(SREBPs). Capable of retaining the SCAP-SREBF2 complex in the ER thus preventing it from escorting SREBPs to the Golgi. Seems to regulate the ubiquitin-mediated proteasomal degradation of HMGCR.
- Molekulargewicht
- 30 kDa
- Gen-ID
- 51141
- UniProt
- Q9Y5U4
- Pathways
- ER-Nucleus Signaling
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