IMPA1 Antikörper
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- Target Alle IMPA1 Antikörper anzeigen
- IMPA1 (Inositol(myo)-1(or 4)-Monophosphatase 1 (IMPA1))
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Reaktivität
- Human, Maus, Ratte
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser IMPA1 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)
- Immunogen
- inositol(myo)-1(or 4)-monophosphatase 1
- Isotyp
- IgG
- Top Product
- Discover our top product IMPA1 Primärantikörper
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- Applikationshinweise
- Optimal working dilution should be determined by the investigator.
- Kommentare
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human kidney tissue were subjected to SDS PAGE followed by western blot with FNab04300(IMPA1 antibody) at dilution of 1:300
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Buffer
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freeze / thaw cycles.
- Lagerung
- -20 °C
- Haltbarkeit
- 12 months
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- Target
- IMPA1 (Inositol(myo)-1(or 4)-Monophosphatase 1 (IMPA1))
- Andere Bezeichnung
- IMPA1 (IMPA1 Produkte)
- Synonyme
- zgc:100926 antikoerper, 2610002K09Rik antikoerper, 2900059K10Rik antikoerper, AI325909 antikoerper, IMP antikoerper, IMPA antikoerper, impa antikoerper, inositol monophosphatase 1 antikoerper, inositol(myo)-1(or 4)-monophosphatase 1 antikoerper, inositol (myo)-1(or 4)-monophosphatase 1 antikoerper, inositol monophosphatase antikoerper, inositol(myo)-1(or 4)-monophosphatase 1 S homeolog antikoerper, impa1 antikoerper, Impa1 antikoerper, IMPA1 antikoerper, impa1.S antikoerper
- Hintergrund
- Synonyms:IMPA Background:This gene encodes an enzyme that dephosphorylates myo-inositol monophosphate to generate free myo-inositol, a precursor of phosphatidylinositol, and is therefore an important modulator of intracellular signal transduction via the production of the second messengers myoinositol 1, 4, 5-trisphosphate and diacylglycerol. This enzyme can also use myo-inositol-1, 3-diphosphate, myo-inositol-1, 4-diphosphate, scyllo-inositol-phosphate, glucose-1-phosphate, glucose-6-phosphate, fructose-1-phosphate, beta-glycerophosphate, and 2'-AMP as substrates. This enzyme shows magnesium-dependent phosphatase activity and is inhibited by therapeutic concentrations of lithium. Inhibition of inositol monophosphate hydroylosis and subsequent depletion of inositol for phosphatidylinositol synthesis may explain the anti- manic and anti- depressive effects of lithium administered to treat bipolar disorder. Alternative splicing results in multiple transcript variants encoding distinct isoforms. A pseudogene of this gene is also present on chromosome 8q21.13.
- Molekulargewicht
- 30 kDa
- Gen-ID
- 3612
- UniProt
- P29218
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