CCDC98 Antikörper
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- Target Alle CCDC98 (FAM175A) Antikörper anzeigen
- CCDC98 (FAM175A) (Family with Sequence Similarity 175, Member A (FAM175A))
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Reaktivität
- Human, Maus, Ratte
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser CCDC98 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Immunohistochemistry (IHC), ELISA
- Immunogen
- family with sequence similarity 175, member A
- Isotyp
- IgG
- Top Product
- Discover our top product FAM175A Primärantikörper
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- Applikationshinweise
- Optimal working dilution should be determined by the investigator.
- Kommentare
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human testis tissue were subjected to SDS PAGE followed by western blot with FNab02974(FAM175A antibody) at dilution of 1:500
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Buffer
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freeze / thaw cycles.
- Lagerung
- -20 °C
- Haltbarkeit
- 12 months
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- Target
- CCDC98 (FAM175A) (Family with Sequence Similarity 175, Member A (FAM175A))
- Andere Bezeichnung
- FAM175A (FAM175A Produkte)
- Synonyme
- CCDC98 antikoerper, abra1 antikoerper, ccdc98 antikoerper, fam175a antikoerper, ABRA1 antikoerper, 3830405G04Rik antikoerper, 5630400M01Rik antikoerper, AI506069 antikoerper, AL024423 antikoerper, AV118690 antikoerper, Ccdc98 antikoerper, RGD1305287 antikoerper, zgc:103522 antikoerper, abraxas 1, BRCA1 A complex subunit antikoerper, Coiled-coil domain-containing protein 98 antikoerper, BRCA1 A complex subunit antikoerper, family with sequence similarity 175 member A antikoerper, abraxas 2a, BRISC complex subunit antikoerper, abraxas 1, BRCA1 A complex subunit S homeolog antikoerper, ABRAXAS1 antikoerper, abraxas1 antikoerper, Abraxas1 antikoerper, FAM175A antikoerper, abraxas2a antikoerper, abraxas1.S antikoerper
- Hintergrund
- Synonyms:ABRA1, CCDC98 Background:Involved in DNA damage response and double-strand break(DSB) repair. Component of the BRCA1-A complex, acting as a central scaffold protein that assembles the various components of the complex and mediates the recruitment of BRCA1. The BRCA1-A complex specifically recognizes 'Lys-63'-linked ubiquitinated histones H2A and H2AX at DNA lesion sites, leading to target the BRCA1-BARD1 heterodimer to sites of DNA damage at DSBs. This complex also possesses deubiquitinase activity that specifically removes 'Lys-63'-linked ubiquitin on histones H2A and H2AX.
- Molekulargewicht
- 46 kDa
- Gen-ID
- 84142
- UniProt
- Q6UWZ7
- Pathways
- DNA Reparatur, Positive Regulation of Response to DNA Damage Stimulus
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