TEX14 Antikörper
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- Target Alle TEX14 Antikörper anzeigen
- TEX14 (Testis Expressed 14 (TEX14))
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Reaktivität
- Human, Maus
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser TEX14 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunoprecipitation (IP)
- Immunogen
- testis expressed 14
- Isotyp
- IgG
- Top Product
- Discover our top product TEX14 Primärantikörper
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- Applikationshinweise
- Optimal working dilution should be determined by the investigator.
- Kommentare
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mouse testis tissue were subjected to SDS PAGE followed by western blot with FNab08609(TEX14 antibody) at dilution of 1:500
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Buffer
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freeze / thaw cycles.
- Lagerung
- -20 °C
- Haltbarkeit
- 12 months
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- Target
- TEX14 (Testis Expressed 14 (TEX14))
- Andere Bezeichnung
- TEX14 (TEX14 Produkte)
- Synonyme
- CT113 antikoerper, C85585 antikoerper, testis expressed 14, intercellular bridge forming factor antikoerper, testis expressed gene 14 antikoerper, inactive serine/threonine-protein kinase TEX14 antikoerper, TEX14 antikoerper, Tex14 antikoerper, tex14 antikoerper, LOC100389169 antikoerper
- Hintergrund
- Synonyms:SGK307 Background:Required both for the formation of intercellular bridges during meiosis and for kinetochore-microtubule attachment during mitosis. Intercellular bridges are evolutionarily conserved structures that connect differentiating germ cells and are required for spermatogenesis and male fertility. Acts by promoting the conversion of midbodies into intercellular bridges via its interaction with CEP55: interaction with CEP55 inhibits the interaction between CEP55 and PDCD6IP/ALIX and TSG101, blocking cell abscission and leading to transform midbodies into intercellular bridges. Also plays a role during mitosis: recruited to kinetochores by PLK1 during early mitosis and regulates the maturation of the outer kinetochores and microtubule attachment. Has no protein kinase activity in vitro(By similarity).
- Gen-ID
- 56155
- UniProt
- Q8IWB6
- Pathways
- Maintenance of Protein Location
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