PAN2 Antikörper
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- Target Alle PAN2 Antikörper anzeigen
- PAN2 (PAN2 Poly(A) Specific Ribonuclease Subunit Homolog (PAN2))
- Reaktivität
- Human, Maus, Ratte
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser PAN2 Antikörper ist unkonjugiert
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Applikation
- ELISA, Western Blotting (WB), Immunohistochemistry (IHC)
- Immunogen
- PAN2 poly(A) specific ribonuclease subunit homolog (S. cerevisiae)
- Isotyp
- IgG
- Top Product
- Discover our top product PAN2 Primärantikörper
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- Applikationshinweise
- Optimal working dilution should be determined by the investigator.
- Kommentare
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NIH/3T3 cells were subjected to SDS PAGE followed by western blot with FNab06131(PAN2 antibody) at dilution of 1:300
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Buffer
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freeze / thaw cycles.
- Lagerung
- -20 °C
- Haltbarkeit
- 12 months
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- Target
- PAN2 (PAN2 Poly(A) Specific Ribonuclease Subunit Homolog (PAN2))
- Andere Bezeichnung
- PAN2 (PAN2 Produkte)
- Synonyme
- USP52 antikoerper, 1200014O24Rik antikoerper, AI047843 antikoerper, AW742773 antikoerper, Usp52 antikoerper, mKIAA0710 antikoerper, PAN2 antikoerper, pan2 antikoerper, PAN2 poly(A) specific ribonuclease subunit antikoerper, PAN2 poly(A) specific ribonuclease subunit homolog (S. cerevisiae) antikoerper, PAN2 poly(A) specific ribonuclease subunit S homeolog antikoerper, PAN2 antikoerper, Pan2 antikoerper, pan2.S antikoerper
- Hintergrund
- Synonyms:KIAA0710, USP52 Background:Catalytic subunit of the poly(A)-nuclease(PAN) deadenylation complex, one of two cytoplasmic mRNA deadenylases involved in general and miRNA-mediated mRNA turnover. PAN specifically shortens poly(A) tails of RNA when the poly(A) stretch is bound by poly(A)-binding protein(PABP), which is followed by rapid degradation of the shortened mRNA tails by the CCR4-NOT complex. Deadenylated mRNAs are then degraded by two alternative mechanisms, namely exosome-mediated 3'-5' exonucleolytic degradation, or deadenlyation-dependent mRNA decaping and subsequent 5'-3' exonucleolytic degradation by XRN1.
- Gen-ID
- 9924
- UniProt
- Q504Q3
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