RSPO2 Antikörper
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- Target Alle RSPO2 Antikörper anzeigen
- RSPO2 (R-Spondin 2 (RSPO2))
- Reaktivität
- Human, Maus, Ratte
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser RSPO2 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), ELISA, Immunoprecipitation (IP)
- Immunogen
- R-spondin 2 homolog (Xenopus laevis)
- Isotyp
- IgG
- Top Product
- Discover our top product RSPO2 Primärantikörper
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- Applikationshinweise
- Optimal working dilution should be determined by the investigator.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Buffer
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freeze / thaw cycles.
- Lagerung
- -20 °C
- Haltbarkeit
- 12 months
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- Target
- RSPO2 (R-Spondin 2 (RSPO2))
- Andere Bezeichnung
- RSPO2 (RSPO2 Produkte)
- Synonyme
- RGD1562331 antikoerper, CRISTIN2 antikoerper, 2610028F08Rik antikoerper, AA673245 antikoerper, D430027K22 antikoerper, ftls antikoerper, R-spondin 2 antikoerper, R-spondin 2 L homeolog antikoerper, Rspo2 antikoerper, rspo2.L antikoerper, rspo2 antikoerper, RSPO2 antikoerper
- Hintergrund
- Synonyms:CRISTIN2, hRspo2, R spondin 2, Roof plate specific spondin 2, RSPO2 Background:Activator of the canonical Wnt signaling pathway by acting as a ligand for LGR4-6 receptors. Upon binding to LGR4-6(LGR4, LGR5 or LGR6), LGR4-6 associate with phosphorylated LRP6 and frizzled receptors that are activated by extracellular Wnt receptors, triggering the canonical Wnt signaling pathway to increase expression of target genes. Also regulates the canonical Wnt/beta-catenin-dependent pathway and non-canonical Wnt signaling by acting as an inhibitor of ZNRF3, an important regulator of the Wnt signaling pathway. Probably also acts as a ligand for frizzled and LRP receptors.
- Gen-ID
- 340419
- UniProt
- Q6UXX9
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