MSL1 Antikörper
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- Target Alle MSL1 Antikörper anzeigen
- MSL1 (Male-Specific Lethal 1 Homolog (MSL1))
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser MSL1 Antikörper ist unkonjugiert
- Applikation
- Western Blotting (WB), ELISA
- Immunogen
- male-specific lethal 1 homolog (Drosophila)
- Isotyp
- IgG
- Top Product
- Discover our top product MSL1 Primärantikörper
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- Applikationshinweise
- Optimal working dilution should be determined by the investigator.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Buffer
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freeze / thaw cycles.
- Lagerung
- -20 °C
- Haltbarkeit
- 12 months
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- Target
- MSL1 (Male-Specific Lethal 1 Homolog (MSL1))
- Andere Bezeichnung
- MSL1 (MSL1 Produkte)
- Synonyme
- MSL-1 antikoerper, hMSL1 antikoerper, 2810017F12Rik antikoerper, 4121402D02Rik antikoerper, 4930463F05Rik antikoerper, AA682082 antikoerper, Msl-1 antikoerper, male specific lethal 1 homolog antikoerper, male-specific lethal 1 homolog (Drosophila) antikoerper, MSL1 antikoerper, Msl1 antikoerper
- Hintergrund
- Synonyms:MSL1L1 Background:Component of histone acetyltransferase complex responsible for the majority of histone H4 acetylation at 'Lys-16'(H4K16ac) which is implicated in the formation of higher-order chromatin structure. Greatly enhances MSL2 E3 ubiquitin ligase activity, promoting monoubiquitination of histone H2B at 'Lys-34'(H2BK34Ub). This modification in turn stimulates histone H3 methylation at 'Lys-4'(H3K4me) and 'Lys-79'(H3K79me) and leads to gene activation, including that of HOXA9 and MEIS1. In the MSL complex, acts as a scaffold to tether MSL3 and KAT8 together for enzymatic activity regulation.
- Molekulargewicht
- 67 kDa
- Gen-ID
- 339287
- UniProt
- Q68DK7
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