TBC1D5 Antikörper
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- Target Alle TBC1D5 Antikörper anzeigen
- TBC1D5 (TBC1 Domain Family, Member 5 (TBC1D5))
- Reaktivität
- Human, Maus, Ratte
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser TBC1D5 Antikörper ist unkonjugiert
- Applikation
- Western Blotting (WB), ELISA, Immunoprecipitation (IP), Immunohistochemistry (IHC)
- Immunogen
- TBC1 domain family, member 5
- Isotyp
- IgG
- Top Product
- Discover our top product TBC1D5 Primärantikörper
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- Applikationshinweise
- Optimal working dilution should be determined by the investigator.
- Kommentare
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A431 cells were subjected to SDS PAGE followed by western blot with FNab08515(TBC1D5 antibody) at dilution of 1:400
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Buffer
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freeze / thaw cycles.
- Lagerung
- -20 °C
- Haltbarkeit
- 12 months
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- Target
- TBC1D5 (TBC1 Domain Family, Member 5 (TBC1D5))
- Andere Bezeichnung
- TBC1D5 (TBC1D5 Produkte)
- Synonyme
- RGD1561626 antikoerper, 1600014N05Rik antikoerper, mKIAA0210 antikoerper, TBC1 domain family, member 5 antikoerper, TBC1 domain family member 5 antikoerper, Tbc1d5 antikoerper, TBC1D5 antikoerper
- Hintergrund
- Synonyms:KIAA0210 Background:May act as a GTPase-activating protein(GAP) for Rab family protein(s). May act as a GAP for RAB7A. Can displace RAB7A and retromer CSC subcomplex from the endosomal membrane to the cytosol, at least retromer displacement seems to require its catalytic activity(PubMed:19531583, PubMed:20923837). Required for retrograde transport of cargo proteins from endosomes to the trans-Golgi network(TGN), the function seems to require its catalytic activity. Involved in regulation of autophagy(PubMed:22354992). May act as a molecular switch between endosomal and autophagosomal transport and is involved in reprogramming vesicle trafficking upon autophagy induction. Involved in the trafficking of ATG9A upon activation of autophagy. May regulate the recruitment of ATG9A-AP2-containing vesicles to autophagic membranes(PubMed:24603492).
- Gen-ID
- 9779
- UniProt
- Q92609
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