ALKBH7 Antikörper
-
- Target Alle ALKBH7 Antikörper anzeigen
- ALKBH7 (AlkB, Alkylation Repair Homolog 7 (ALKBH7))
- Reaktivität
- Human, Maus, Ratte
-
Wirt
- Kaninchen
-
Klonalität
- Polyklonal
-
Konjugat
- Dieser ALKBH7 Antikörper ist unkonjugiert
- Applikation
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
- Immunogen
- alkB, alkylation repair homolog 7 (E. coli)
- Isotyp
- IgG
- Top Product
- Discover our top product ALKBH7 Primärantikörper
-
-
- Applikationshinweise
- WB :1:200-1:2000,IHC:1:20-1:200
- Kommentare
-
human testis tissue were subjected to SDS PAGE followed by western blot with FNab00315(ALKBH7 antibody) at dilution of 1:500
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
- Buffer
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freeze / thaw cycles.
- Lagerung
- -20 °C
- Haltbarkeit
- 12 months
-
- Target
- ALKBH7 (AlkB, Alkylation Repair Homolog 7 (ALKBH7))
- Andere Bezeichnung
- ALKBH7 (ALKBH7 Produkte)
- Synonyme
- ABH7 antikoerper, SPATA11 antikoerper, UNQ6002 antikoerper, 2310045B01Rik antikoerper, 2510008E23Rik antikoerper, Abh7 antikoerper, Spata11 antikoerper, alkB homolog 7 antikoerper, Alkbh7 antikoerper, ALKBH7 antikoerper
- Hintergrund
- Synonyms:ABH7, ALKBH7, SPATA11, UNQ6002 Background:May function as protein hydroxylase, can catalyze auto-hydroxylation at Leu-110(in vitro), but this activity may be due to the absence of the true substrate(PubMed:25122757). Required to induce programmed necrosis in response to DNA damage caused by cytotoxic alkylating agents. Acts by triggering the collapse of mitochondrial membrane potential and loss of mitochondrial function that leads to energy depletion and cell death(PubMed:23666923). ALKBH7-mediated necrosis is probably required to prevent the accumulation of cells with DNA damage(PubMed:23666923). Does not display DNA demethylase activity(PubMed:23666923). Involved in fatty acid metabolism(By similarity).
- Molekulargewicht
- 25kDa
- Gen-ID
- 84266
- UniProt
- Q9BT30
-