NKX2-1 Antikörper
-
- Target Alle NKX2-1 Antikörper anzeigen
- NKX2-1 (NK2 Homeobox 1 (NKX2-1))
-
Reaktivität
- Human, Maus, Ratte
-
Wirt
- Kaninchen
-
Klonalität
- Monoklonal
-
Konjugat
- Dieser NKX2-1 Antikörper ist unkonjugiert
-
Applikation
- Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Aufreinigung
- Purified
- Reinheit
- Protein A affinity chromatography
- Immunogen
- Recombinant protein was used as the immunogen for the recombinant NKX2.1 antibody.
- Klon
- NX2-1-1855R
- Isotyp
- IgG kappa
- Top Product
- Discover our top product NKX2-1 Primärantikörper
-
-
- Applikationshinweise
-
Optimal dilution of the recombinant NKX2.1 antibody should be determined by the researcher.
1. The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min.\. Immunohistochemistry (FFPE): 0.5-1 μg/mL for 30 min at RT,Prediluted IHC only format: incubate for 30 min at RT (1) - Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
- Buffer
- 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C,-20 °C
- Informationen zur Lagerung
- Store the recombinant NKX2.1 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
-
- Target
- NKX2-1 (NK2 Homeobox 1 (NKX2-1))
- Andere Bezeichnung
- NKX2.1 / TTF1 (NKX2-1 Produkte)
- Synonyme
- BCH antikoerper, BHC antikoerper, NK-2 antikoerper, NKX2.1 antikoerper, NKX2A antikoerper, TEBP antikoerper, TITF1 antikoerper, TTF-1 antikoerper, TTF1 antikoerper, titf1-A antikoerper, Xnkx-2.1 antikoerper, NKX2-1 antikoerper, LOC100227803 antikoerper, AV026640 antikoerper, Nkx2.1 antikoerper, T/EBP antikoerper, Titf1 antikoerper, Ttf-1 antikoerper, nk2.1a antikoerper, nkx2.1 antikoerper, nkx2.4a antikoerper, titf1 antikoerper, titf1a antikoerper, NK2 homeobox 1 antikoerper, NK2 homeobox 1 L homeolog antikoerper, NK2 homeobox 4b antikoerper, NKX2-1 antikoerper, nkx2-1.L antikoerper, Nkx2-1 antikoerper, nkx2.4b antikoerper
- Hintergrund
- NKX2.1/TTF1 is a member of the NKx2 family of homeodomain transcription factors. It is expressed in epithelial cells of the thyroid gland and the lung. Nuclei from liver, stomach, pancreas, small intestine, colon, kidney, breast, skin, testes, pituitary, prostate, and adrenal glands are unreactive. Anti-NKX2.1 is useful in differentiating primary adenocarcinoma of the lung from metastatic carcinomas originating in the breast, mediastinal germ cell tumors, and malignant mesothelioma. It can also be used to differentiate small cell lung carcinoma from lymphoid infiltrates. Loss of NKX2.1 expression in non-small cell lung carcinoma has been associated with aggressive behavior of such neoplasms. NKX2.1 reactivity is also seen in thyroid malignancies.
- Pathways
- Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Systemic Arterial Blood Pressure by Hormones, Cellular Glucan Metabolic Process, Feeding Behaviour
-