PDK1 Antikörper (AA 107-336)

Produktnummer ABIN5708184

Produktdetails anti-PDK1 Antikörper

Target: PDK1 (Pyruvate Dehydrogenase Kinase 1 (PDK1))

Bindungsspezifität: AA 107-336

Reaktivität: Human, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PDK1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Aufreinigung: Antigen affinity purified

Immunogen: A recombinant human protein corresponding to amino acids V107-Y336 was used as the immunogen for the PDK1 antibody.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the PDK1 antibody should be determined by the researcher.\. Western blot: 0.5-1 μg/mL, IHC (FFPE): 1-2 μg/mL, Direct ELISA: 0.1-0.5 μg/mL

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Lagerung: -20 °C

Informationen zur Lagerung: After reconstitution, the PDK1 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Details zu PDK1

Target: PDK1 (Pyruvate Dehydrogenase Kinase 1 (PDK1))

Andere Bezeichnung: PDK1 / Pyruvate Dehydrogenase Kinase 1 (PDK1 Produkte)

Synonyme: ATP5A antikoerper, B830012B01 antikoerper, D530020C15Rik antikoerper, si:zfos-979f1.3 antikoerper, 3-phosphoinositide dependent protein kinase-1 antikoerper, pyruvate dehydrogenase kinase 1 antikoerper, ATP synthase, H+ transporting, mitochondrial Fo complex subunit C2 (subunit 9) antikoerper, pyruvate dehydrogenase kinase, isoenzyme 1 antikoerper, pyruvate dehydrogenase kinase, isozyme 1 antikoerper, pyruvate dehydrogenase kinase 1 L homeolog antikoerper, Pdpk1 antikoerper, PDK1 antikoerper, ATP5G2 antikoerper, Pdk1 antikoerper, pdk1 antikoerper, pdk1.L antikoerper

Hintergrund: PDK1 (Pyruvate Dehydrogenase Kinase Isoenzyme 1), is an enzyme that in humans is encoded by the PDK1 gene. To find human PDKs, Gudi et al. (1995) used oligonucleotide primers to screen a human liver cDNA library by PCR. They identified and reported the deduced amino acid sequences of PDK1, PDK2, and PDK3. The human PDK1 gene encodes a protein with a predicted molecular mass of 49,244 Da that shares 93 % identity with that of the rat PDK1 gene. Northern blot analysis showed that the PDK1 message was expressed predominantly in the heart.

UniProt: Q15118

Pathways: PI3K-Akt Signalweg, RTK Signalweg, Regulation of Carbohydrate Metabolic Process, Hepatitis C, Warburg Effekt