NLRP3 Antikörper (N-Term)

Produktnummer ABIN570839

Produktdetails anti-NLRP3 Antikörper

Target: NLRP3 (NLR Family, Pyrin Domain Containing 3 (NLRP3))

Bindungsspezifität: N-Term

Reaktivität: Human

Wirt: Ziege

Klonalität: Polyklonal

Konjugat: Dieser NLRP3 Antikörper ist unkonjugiert

Applikation: ELISA, Immunohistochemistry (IHC)

Verwendungszweck: Cryopirin / NALP3 / NLRP3

Sequenz: RDLYEKAKRD EPK

Spezifität: This antibody is expected to recognize all reported isoforms (NP_004886.3, NP_899632.1, NP_001120933.1, NP_001120934.1). Reported variants NP_001073289.1 and NP_004886.3 represent identical protein.

Kreuzreaktivität: Human

Aufreinigung: Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.

Güteklasse: Verified

Immunogen: Peptide with sequence RDLYEKAKRDEPK-C, from the N-Terminus (near) of the protein sequence according to NP_004886.3, NP_899632.1, NP_001120933.1, NP_001120934.1.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise:

Immunohistochemistry: Paraffin embedded Human peripheral blood leukocytes. Recommended concentration: 5 μg/mL.

Western Blot: Preliminary experiments gave an approx 36 kDa band in Human Peripheral Blood Mononucleocytes lysates and in lysates of cell line MOLT4, after 0.3-1 μg/mL antibody staining. Please note that currently we cannot find an explanation in the liter

Peptide ELISA: antibody detection limit dilution 1:32000.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Supplied at 0.5 mg/mL in Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Minimize freezing and thawing.

Lagerung: -20 °C

Informationen zur Lagerung: Aliquot and store at -20°C, with minimal freeze/thawing. A working aliquot may be refrigerated at 4°C for a few weeks and still remain viable.

Details zu NLRP3

Target: NLRP3 (NLR Family, Pyrin Domain Containing 3 (NLRP3))

Andere Bezeichnung: NLRP3 (NLRP3 Produkte)

Synonyme: CIAS1 antikoerper, Nalp3 antikoerper, avp antikoerper, cias1 antikoerper, nalp3 antikoerper, pypaf1 antikoerper, agtavprl antikoerper, AGTAVPRL antikoerper, AII antikoerper, AVP antikoerper, C1orf7 antikoerper, CLR1.1 antikoerper, FCAS antikoerper, FCU antikoerper, MWS antikoerper, NALP3 antikoerper, PYPAF1 antikoerper, AII/AVP antikoerper, Cias1 antikoerper, Mmig1 antikoerper, Pypaf1 antikoerper, NLR family pyrin domain containing-like antikoerper, NLR family pyrin domain containing 3 antikoerper, NLR family, pyrin domain containing 3 L homeolog antikoerper, NLR family, pyrin domain containing 3 antikoerper, NLRPL antikoerper, NLRP3 antikoerper, nlrp3.L antikoerper, Nlrp3 antikoerper

Hintergrund: NLRP3, NLR family, pyrin domain containing 3, AGTAVPRL, AII, AII/AVP, AVP, C1orf7, CIAS1, CLR1.1, FCAS, FCU, FLJ95925, MWS, NALP3, PYPAF1, AII/AVP receptor-like, NACHT domain-, leucine-rich repeat-, and PYD-containing protein 3, NACHT, LRR and PYD contain

Gen-ID: 114548

NCBI Accession: NP_004886, NP_899632, NP_001120933, NP_001120934

Pathways: Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Endopeptidase Activity, Inflammasome