WWOX Antikörper

Produktnummer ABIN5708495

Produktdetails anti-WWOX Antikörper

Target: WWOX (WW Domain Containing Oxidoreductase (WWOX))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser WWOX Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Aufreinigung: Antigen affinity purified

Immunogen: A recombinant human protein corresponding to amino acids M1-D245 was used as the immunogen for the WWOX antibody.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the WWOX antibody should be determined by the researcher.\. Western blot: 0.5-1 μg/mL, IHC (FFPE): 1-2 μg/mL, Direct ELISA: 0.1-0.5 μg/mL

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Lagerung: -20 °C

Informationen zur Lagerung: After reconstitution, the WWOX antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Details zu WWOX

Target: WWOX (WW Domain Containing Oxidoreductase (WWOX))

Andere Bezeichnung: WWOX (WWOX Produkte)

Synonyme: CG7221 antikoerper, DmWWOX antikoerper, Dmel\\CG7221 antikoerper, anon-EST:Posey177 antikoerper, GB11795 antikoerper, WWOX antikoerper, D16S432E antikoerper, FOR antikoerper, FRA16D antikoerper, HHCMA56 antikoerper, PRO0128 antikoerper, SDR41C1 antikoerper, WOX1 antikoerper, zgc:55975 antikoerper, 5330426P09Rik antikoerper, 9030416C10Rik antikoerper, WW domain containing oxidoreductase antikoerper, WW domain-containing oxidoreductase antikoerper, Wwox antikoerper, LOC411815 antikoerper, WWOX antikoerper, CpipJ_CPIJ004939 antikoerper, MCYG_01584 antikoerper, VDBG_05631 antikoerper, VDBG_01326 antikoerper, VDBG_06753 antikoerper, Tsp_03967 antikoerper, LOC100284583 antikoerper, wwox antikoerper

Hintergrund: WW domain-containing oxidoreductase is an enzyme that in humans is encoded by the WWOX gene. This gene encodes a member of the short-chain dehydrogenases/reductases (SDR) protein family. It spans the FRA16D common chromosomal fragile site and appears to function as a tumor suppressor gene. Expression of the encoded protein is able to induce apoptosis, while defects in this gene are associated with multiple types of cancer. Disruption of this gene is also associated with autosomal recessive spinocerebellar ataxia 12. Disruption of a similar gene in mouse results in impaired steroidogenesis, additionally suggesting a metabolic function for the protein. Alternative splicing results in multiple transcript variants.

UniProt: Q9NZC7