TET2 Antikörper (Internal Region)

Produktnummer ABIN571057

Produktdetails anti-TET2 Antikörper

Target: TET2 (Tet Methylcytosine Dioxygenase 2 (TET2))

Bindungsspezifität: Internal Region

Reaktivität: Human

Wirt: Ziege

Klonalität: Polyklonal

Konjugat: Dieser TET2 Antikörper ist unkonjugiert

Applikation: ELISA, Immunohistochemistry (IHC), Flow Cytometry (FACS)

Verwendungszweck: TET2

Sequenz: PHPQSNNDQQ REGSF

Spezifität: This antibody is expected to recognize both reported isoforms (NP_001120680.1, NP_060098.3).

Kreuzreaktivität: Hund, Human, Maus

Aufreinigung: Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.

Güteklasse: Verified

Immunogen: C-PHPQSNNDQQREGSF

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise:

Immunohistochemistry: In paraffin embedded Human Spleen shows nuclear staining in select splenocytes. Recommended concentration: 2-6 μg/mL.

Peptide ELISA: antibody detection limit dilution 1:16000.

Kommentare:

Flow Cytometry: Flow cytometric analysis of A431 cells. Recommended concentration: 10ug/ml.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Supplied at 0.5 mg/mL in Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Minimize freezing and thawing.

Lagerung: -20 °C

Informationen zur Lagerung: Aliquot and store at -20°C, with minimal freeze/thawing. A working aliquot may be refrigerated at 4°C for a few weeks and still remain viable.

Referenzen für anti-TET2 Antikörper (ABIN571057)

Orr, Haffner, Nelson, Yegnasubramanian, Eberhart: "Decreased 5-hydroxymethylcytosine is associated with neural progenitor phenotype in normal brain and shorter survival in malignant glioma." in: PLoS ONE, Vol. 7, Issue 7, pp. e41036, (2012) (PubMed).

Details zu TET2

Target: TET2 (Tet Methylcytosine Dioxygenase 2 (TET2))

Andere Bezeichnung: TET2 (TET2 Produkte)

Synonyme: KIAA1546 antikoerper, MDS antikoerper, Ayu17-449 antikoerper, E130014J05Rik antikoerper, mKIAA1546 antikoerper, RGD1311625 antikoerper, tet methylcytosine dioxygenase 2 antikoerper, TET2 antikoerper, Tet2 antikoerper

Hintergrund: TET2, tet oncogene family member 2, FLJ20032, KIAA1546, MGC125715, OTTHUMP00000161869

Gen-ID: 54790, 214133

NCBI Accession: NP_001120680, NP_060098

Pathways: Warburg Effekt