Reticulon 4 Antikörper (AA 501-515)
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- Target Alle Reticulon 4 (RTN4) Antikörper anzeigen
- Reticulon 4 (RTN4)
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Bindungsspezifität
- AA 501-515
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Reaktivität
- Human, Affe
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Wirt
- Ziege
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Klonalität
- Polyklonal
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Konjugat
- Dieser Reticulon 4 Antikörper ist unkonjugiert
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Applikation
- Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Marke
- IHC-plus™
- Spezifität
- Human RTN4 / Nogo. This antibody is expected to recognize reported isoform A (NP_065393.1) and isoform E (NP_997404.1).
- Homologie
- Percent identity by BLAST analysis: Human, Gorilla, Monkey (100%) Gibbon, Panda, Horse (93%) Marmoset, Dog, Bovine, Rabbit (87%) Mouse, Rat, Bat, Pig (80%).
- Aufreinigung
- Immunoaffinity purified
- Immunogen
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Synthetic peptide C-KAQIVTEKNTSTKTS from an internal region of human RTN4 / Nogo (NP_065393.1, NP_997404.1). Percent identity by BLAST analysis: Human, Gorilla, Monkey (100%), Gibbon, Panda, Horse (93%), Marmoset, Dog, Bovine, Rabbit (87%), Mouse, Rat, Bat, Pig (80%).
Type of Immunogen: Synthetic peptide
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- Applikationshinweise
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Approved: IHC, IHC-P (2.5 μg/mL)
Usage: Immunohistochemistry: This antibody was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen. The stained slides were evaluated by a pathologist to confirm staining specificity. The optimal working concentration for this antibody was determined to be 2.5 to 5 μg/mL - Kommentare
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Target Species of Antibody: Human
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- Lot specific
- Buffer
- Tris-buffered saline, pH 7.3, 0.5 % BSA, 0.02 % sodium azide
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Minimize freezing and thawing.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20°C. Avoid freeze-thaw cycles.
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- Target
- Reticulon 4 (RTN4)
- Andere Bezeichnung
- RTN4 / Nogo (RTN4 Produkte)
- Hintergrund
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Name/Gene ID: RTN4
Family: Reticulon
Synonyms: RTN4, Human NogoA, My043 protein, Neurite outgrowth inhibitor, NOGOC, NSP-CL, Nogo protein, KIAA0886, Reticulon 5, Reticulon-4, Reticulon-5, Reticulon 4, RTN4-B1, RTN-X, RTN4-A, RTN4-B2, RTN4-C, Nbla00271, Neurite growth inhibitor 220, NI220/250, NOGO-A, Nogo-C, ASY, Foocen, Nbla10545, NOGO, Nogo-B, NSP - Gen-ID
- 57142
- NCBI Accession
- NP_065393, NP_997404
- UniProt
- Q9NQC3
- Pathways
- Neurotrophin Signalübertragung, Regulation of Cell Size, SARS-CoV-2 Protein Interaktom
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