Caspase 5 p20 Antikörper (Cleaved-Asp121)

Produktnummer ABIN5955946

Produktdetails anti-Caspase 5 p20 Antikörper

Target: Caspase 5 p20

Bindungsspezifität: Cleaved-Asp121

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Caspase 5 p20 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Spezifität: Apoptosis related cysteine protease,CASP-5,CASP5,CASP5,Caspase-5 subunit p10,ICE(rel)-III,ICERELIII,ICH 3,ICH 3 protease,Protease ICH-3,Protease TY,TY,TY protease

Aufreinigung: Affinity purification

Immunogen: Synthesized peptide derived from the Internal region of human Caspase-5 p20

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500-1:2000, ELISA 1:20000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 0.5 % BSA and 50 % glycerol,  pH 7.4

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu Caspase 5 p20

Target: Caspase 5 p20

Andere Bezeichnung: Caspase-5 p20 (Caspase 5 p20 Produkte)

Hintergrund: This gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. Overexpression of the active form of this enzyme induces apoptosis in fibroblasts. Max, a central component of the Myc/Max/Mad transcription regulation network important for cell growth, differentiation, and apoptosis, is cleaved by this protein, this process requires Fas-mediated dephosphorylation of Max. The expression of this gene is regulated by interferon-gamma and lipopolysaccharide. Alternatively spliced transcript variants have been identified for this gene.

Molekulargewicht: 48kDa

Gen-ID: 838

UniProt: P51878