CD316,CD316 antigen,CD81 partner 3,CD81P3,EWI-2,EWI2,Glu-Trp-Ile EWI motif-containing protein 2,igsf-8,IgSF8,IGSF8,Immunoglobulin superfamily member 8,Immunoglobulin superfamily member 8 precursor,KCT-4,KCT4,Keratinocytes-associated transmembrane protein 4,LIR-D1,PGRL,Prostaglandin regulatory-like protein
Aufreinigung
Affinity purification
Immunogen
Synthesized peptide derived from the Internal region of human CD316.
May play a key role in diverse functions ascribed to CD81 and CD9 such as oocytes fertilization or hepatitis C virus function. May regulate proliferation and differentiation of keratinocytes. May be a negative regulator of cell motility: suppresses T-cell mobility coordinately with CD81, associates with CD82 to suppress prostate cancer cell migration, regulates epidermoid cell reaggregation and motility on laminin-5 with CD9 and CD81 as key linkers. May also play a role on integrin-dependent morphology and motility functions. May participate in the regulation of neurite outgrowth and maintenance of the neural network in the adult brain.