THRAP3 Antikörper
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- Target Alle THRAP3 Antikörper anzeigen
- THRAP3 (Thyroid Hormone Receptor Associated Protein 3 (THRAP3))
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser THRAP3 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB)
- Kreuzreaktivität
- Human, Maus
- Produktmerkmale
- Polyclonal Antibodies
- Immunogen
- A synthetic peptide of human THRAP3
- Isotyp
- IgG
- Top Product
- Discover our top product THRAP3 Primärantikörper
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- Applikationshinweise
- WB,1:500 - 1:1000
- Kommentare
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HIGH QUALITY
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20°C. Avoid freeze / thaw cycles.
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- Target
- THRAP3 (Thyroid Hormone Receptor Associated Protein 3 (THRAP3))
- Andere Bezeichnung
- THRAP3 (THRAP3 Produkte)
- Synonyme
- TRAP150 antikoerper, 9330151F09Rik antikoerper, B230333E16Rik antikoerper, Trap150 antikoerper, trap150 antikoerper, Thrap3 antikoerper, MGC132228 antikoerper, zgc:85716 antikoerper, thyroid hormone receptor associated protein 3 antikoerper, DNA cross-link repair 1A protein antikoerper, thyroid hormone receptor associated protein 3 S homeolog antikoerper, thyroid hormone receptor-associated protein 3 antikoerper, thyroid hormone receptor associated protein 3b antikoerper, THRAP3 antikoerper, CpipJ_CPIJ018886 antikoerper, CpipJ_CPIJ019503 antikoerper, Thrap3 antikoerper, thrap3 antikoerper, thrap3.S antikoerper, thrap3b antikoerper
- Hintergrund
- Involved in pre-mRNA splicing. Remains associated with spliced mRNA after splicing which probably involves interactions with the exon junction complex (EJC. Can trigger mRNA decay which seems to be independent of nonsense-mediated decay involving premature stop codons (PTC recognition. May be involved in nuclear mRNA decay. Involved in regulation of signal-induced alternative splicing. During splicing of PTPRC/CD45 is proposed to sequester phosphorylated SFPQ from PTPRC/CD45 pre-mRNA in resting T-cells. Involved in cyclin-D1/CCND1 mRNA stability probably by acting as component of the SNARP complex which associates with both the 3'end of the CCND1 gene and its mRNA. Involved in response to DNA damage. Is excluced from DNA damage sites in a manner that parallels transcription inhibition, the function may involve the SNARP complex. Initially thought to play a role in transcriptional coactivation through its association with the TRAP complex, however, it is not regarded as a stable Mediator complex subunit. Cooperatively with HELZ2, enhances the transcriptional activation mediated by PPARG, maybe through the stabilization of the PPARG binding to DNA in presence of ligand. May play a role in the terminal stage of adipocyte differentiation. Plays a role in the positive regulation of the circadian clock. Acts as a coactivator of the CLOCK-ARNTL/BMAL1 heterodimer and promotes its transcriptional activator activity and binding to circadian target genes.,THRAP3,TRAP150,BCLAF2,Epigenetics & Nuclear Signaling,RNA Binding,Nuclear Receptor Signaling,Nuclear hormone receptors,Signal Transduction,THRAP3
- Molekulargewicht
- 108 kDa
- Gen-ID
- 9967
- UniProt
- Q9Y2W1
- Pathways
- Intracellular Steroid Hormone Receptor Signaling Pathway
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