GRK1 Antikörper (AA 1-160)

Produktnummer ABIN6134352

Produktdetails anti-GRK1 Antikörper

Target: GRK1 (G Protein-Coupled Receptor Kinase 1 (GRK1))

Bindungsspezifität: AA 1-160

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GRK1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Sequenz: MDFGSLETVV ANSAFIAARG SFDGSSSQPS RDKKYLAKLK LPPLSKCESL RDSLSLEFES VCLEQPIGKK LFQQFLQSAE KHLPALELWK DIEDYDTADN DLQPQKAQTI LAQYLDPQAK LFCSFLDEGI VAKFKEGPVE IQDGLFQPLL QATLAHLGQA

Kreuzreaktivität: Human, Maus, Ratte

Produktmerkmale: Polyclonal Antibodies

Aufreinigung: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-160 of human GRK1 (NP_002920.1).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:200 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Referenzen für anti-GRK1 Antikörper (ABIN6134352)

Liu, Chen, Yu, Raghupathy, Liu, Qin, Li, Huang, Liao, Wang, Zou, Shu, Tang, Liu: "Knockout of RP2 decreases GRK1 and rod transducin subunits and leads to photoreceptor degeneration in zebrafish." in: Human molecular genetics, Vol. 24, Issue 16, pp. 4648-59, (2015) (PubMed).

Details zu GRK1

Target: GRK1 (G Protein-Coupled Receptor Kinase 1 (GRK1))

Andere Bezeichnung: GRK1 (GRK1 Produkte)

Synonyme: GPRK1 antikoerper, RHOK antikoerper, RK antikoerper, Gprk1 antikoerper, Rhok antikoerper, Rk antikoerper, CG40129 antikoerper, CT4320 antikoerper, Dmel\\CG40129 antikoerper, Gprk-1 antikoerper, Rok antikoerper, gprk1 antikoerper, grk1 antikoerper, zgc:112194 antikoerper, G protein-coupled receptor kinase 1 antikoerper, G protein-coupled receptor kinase 1 a antikoerper, G protein-coupled receptor kinase 1 b antikoerper, GRK1 antikoerper, Grk1 antikoerper, Gprk1 antikoerper, grk1a antikoerper, grk1b antikoerper

Hintergrund: This gene encodes a member of the guanine nucleotide-binding protein (G protein)-coupled receptor kinase subfamily of the Ser/Thr protein kinase family. The protein phosphorylates rhodopsin and initiates its deactivation. Defects in GRK1 are known to cause Oguchi disease 2 (also known as stationary night blindness Oguchi type-2).,GRK1,GPRK1,RHOK,RK,Signal Transduction,G protein signaling,G-Protein-Coupled Receptors(GPCR),Kinase,Tyrosine kinases,Neuroscience,GRK1

Molekulargewicht: 63 kDa

Gen-ID: 6011

UniProt: Q15835

Pathways: Regulation of G-Protein Coupled Receptor Protein Signaling, Phototransduction