AGR2 Antikörper (AA 21-175)

Produktnummer ABIN6136646

Produktdetails anti-AGR2 Antikörper

Target: AGR2 (Anterior Gradient Homolog 2 (Xenopus Laevis) (AGR2))

Bindungsspezifität: AA 21-175

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser AGR2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Sequenz: RDTTVKPGAK KDTKDSRPKL PQTLSRGWGD QLIWTQTYEE ALYKSKTSNK PLMIIHHLDE CPHSQALKKV FAENKEIQKL AEQFVLLNLV YETTDKHLSP DGQYVPRIMF VDPSLTVRAD ITGRYSNRLY AYEPADTALL LDNMKKALKL LKTEL

Kreuzreaktivität: Human, Maus, Ratte

Produktmerkmale: Polyclonal Antibodies

Aufreinigung: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 21-175 of human AGR2 (NP_006399.1).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200

Kommentare:

HIGH QUALITY

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu AGR2

Target: AGR2 (Anterior Gradient Homolog 2 (Xenopus Laevis) (AGR2))

Andere Bezeichnung: AGR2 (AGR2 Produkte)

Synonyme: AG2 antikoerper, GOB-4 antikoerper, HAG-2 antikoerper, PDIA17 antikoerper, XAG-2 antikoerper, Agr2h antikoerper, Gob-4 antikoerper, mAG-2 antikoerper, wu:fj29g05 antikoerper, zgc:112187 antikoerper, agr2 antikoerper, hag3 antikoerper, hag-3 antikoerper, bcmp11 antikoerper, MGC89004 antikoerper, XAgr2 antikoerper, agr2-A antikoerper, anterior gradient 2, protein disulphide isomerase family member antikoerper, anterior gradient 2 antikoerper, anterior gradient 3, protein disulphide isomerase family member antikoerper, anterior gradient 2, protein disulphide isomerase family member S homeolog antikoerper, AGR2 antikoerper, Agr2 antikoerper, agr2 antikoerper, agr3 antikoerper, agr2.S antikoerper

Hintergrund: This gene encodes a member of the disulfide isomerase (PDI) family of endoplasmic reticulum (ER) proteins that catalyze protein folding and thiol-disulfide interchange reactions. The encoded protein has an N-terminal ER-signal sequence, a catalytically active thioredoxin domain, and a C-terminal ER-retention sequence. This protein plays a role in cell migration, cellular transformation and metastasis and is as a p53 inhibitor. As an ER-localized molecular chaperone, it plays a role in the folding, trafficking, and assembly of cysteine-rich transmembrane receptors and the cysteine-rich intestinal gylcoprotein mucin. This gene has been implicated in inflammatory bowel disease and cancer progression.,AGR2,AG-2,AG2,GOB-4,HAG-2,HEL-S-116,HPC8,PDIA17,XAG-2,Cancer,Tumor biomarkers,Cell Biology & Developmental Biology,Stem Cells,AGR2

Molekulargewicht: 19 kDa

Gen-ID: 10551

UniProt: O95994