PRAS40 Antikörper (AA 152-276)

Produktnummer ABIN6136741

Produktdetails anti-PRAS40 Antikörper

Target: PRAS40 (AKT1S1) (AKT1 Substrate 1 (Proline-Rich) (AKT1S1))

Bindungsspezifität: AA 152-276

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PRAS40 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Sequenz: DEDATLQDLP PFCESDPEST DDGSLSEETP AGPPTCSVPP ASALPTQQYA KSLPVSVPVW GFKEKRTEAR SSDEENGPPS SPDLDRIAAS MRALVLREAE DTQVFGDLPR PRLNTSDFQK LKRKY

Kreuzreaktivität: Human, Maus, Ratte

Produktmerkmale: Polyclonal Antibodies

Aufreinigung: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 152-276 of human AKT1S1/PRAS40 (NP_115751.3).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000,IHC,1:50 - 1:100,IF,1:50 - 1:100

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu PRAS40

Target: PRAS40 (AKT1S1) (AKT1 Substrate 1 (Proline-Rich) (AKT1S1))

Andere Bezeichnung: AKT1S1 (AKT1S1 Produkte)

Synonyme: MGC81452 antikoerper, lobe antikoerper, pras40 antikoerper, fb34a04 antikoerper, wu:fb34a04 antikoerper, Lobe antikoerper, PRAS40 antikoerper, 1110012J22Rik antikoerper, AI227026 antikoerper, Lobel antikoerper, AKT1 substrate 1 (proline rich) S homeolog antikoerper, AKT1 substrate 1 antikoerper, AKT1 substrate 1 (proline rich) antikoerper, AKT1 substrate 1 (proline-rich) antikoerper, akt1s1.S antikoerper, AKT1S1 antikoerper, akt1s1 antikoerper, Akt1s1 antikoerper

Hintergrund: AKT1S1 is a proline-rich substrate of AKT (MIM 164730) that binds 14-3-3 protein (see YWHAH, MIM 113508) when phosphorylated (Kovacina et al., 2003 [PubMed 12524439]).[supplied by OMIM, Mar 2008],AKT1S1,Lobe,PRAS40,Epigenetics & Nuclear Signaling,Translation Control,Regulation of eIF4 and p70 S6 Kinase,Signal Transduction,Kinase,PI3K-Akt Signaling Pathway,mTOR Signaling Pathway,Cell Biology & Developmental Biology,Apoptosis,Autophagy,Cell Cycle,Endocrine & Metabolism,Insulin Receptor Signaling Pathway,Immunology & Inflammation,T Cell Receptor Signaling Pathway,Neuroscience,Akt downstream targets,AKT1S1

Molekulargewicht: 13 kDa/27 kDa/29 kDa

Gen-ID: 84335

UniProt: Q96B36

Pathways: Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung, Regulation of Cell Size, Autophagie, BCR Signaling, Warburg Effekt