ALKBH5 Antikörper (AA 245-394)

Produktnummer ABIN6136806

Produktdetails anti-ALKBH5 Antikörper

Target: ALKBH5 (AlkB, Alkylation Repair Homolog 5 (ALKBH5))

Bindungsspezifität: AA 245-394

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ALKBH5 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: SLPVRRGSVT VLSGYAADEI THCIRPQDIK ERRAVIILRK TRLDAPRLET KSLSSSVLPP SYASDRLSGN NRDPALKPKR SHRKADPDAA HRPRILEMDK EENRRSVLLP THRRRGSFSS ENYWRKSYES SEDCSEAAGS PARKVKMRRH

Kreuzreaktivität: Human, Maus, Ratte

Produktmerkmale: Polyclonal Antibodies

Aufreinigung: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 245-394 of human ALKBH5 (NP_060228.3).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu ALKBH5

Target: ALKBH5 (AlkB, Alkylation Repair Homolog 5 (ALKBH5))

Andere Bezeichnung: ALKBH5 (ALKBH5 Produkte)

Synonyme: RGD1309496 antikoerper, ABH5 antikoerper, OFOXD antikoerper, OFOXD1 antikoerper, AW050020 antikoerper, AW215868 antikoerper, Abh5 antikoerper, E130207K11 antikoerper, Ofoxd antikoerper, alkB homolog 5, RNA demethylase antikoerper, alkB homolog 5, RNA demethylase L homeolog antikoerper, Alkbh5 antikoerper, alkbh5.L antikoerper, ALKBH5 antikoerper

Hintergrund: Dioxygenase that demethylates RNA by oxidative demethylation: specifically demethylates N(6-methyladenosine (m6A RNA, the most prevalent internal modification of messenger RNA (mRNA in higher eukaryotes. Can also demethylate N(6-methyladenosine in single-stranded DNA (in vitro. Requires molecular oxygen, alpha-ketoglutarate and iron. Demethylation of m6A mRNA affects mRNA processing and export. Required for the late meiotic and haploid phases of spermatogenesis by mediating m6A demethylation in spermatocytes and round spermatids: m6A demethylation of target transcripts is required for correct splicing and the production of longer 3'-UTR mRNAs in male germ cells (By similarity.,ALKBH5,ABH5,OFOXD,OFOXD1,Epigenetics & Nuclear Signaling,DNA Damage & Repair,RNA Binding,ALKBH5

Molekulargewicht: 43 kDa/44 kDa/52 kDa

Gen-ID: 54890

UniProt: Q6P6C2